Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343521 | 0.83 | PDK2 (0.51) | BACE1PDCD1CD274TACR1PDK2 | |
| SCHEMBL343208 | 0.79 | HSD17B10 (0.53) | BACE1PTGDR2CES2TACR1FABP4 | |
| SCHEMBL2367516 | 0.79 | BACE1 (0.55) | BACE1PTGDR2AKR1C3AKR1C2FABP4 | |
| SCHEMBL2302131 | 0.79 | CES2 (0.47) | CES2AKR1C3AKR1C2PDK2 | |
| SCHEMBL28011915 | 0.79 | CA12 (0.64) | CES2 | |
| Hydrochloric Acid SCHEMBL7763180 | 0.78 | HSD17B10 (0.51) | BACE1PTGDR2CES2TACR1FABP4 | |
| SCHEMBL27636054 | 0.78 | SCN1A (0.62) | PDCD1CD274PDK2SCN1ASCN2A | |
| SCHEMBL28662231 | 0.77 | BCAT2 (0.56) | BACE1PTGDR2CES2TACR1FABP4 | |
| SCHEMBL6639339 | 0.77 | PTGDR2 (0.50) | BACE1PTGDR2CES2TACR1FABP4 | |
| SCHEMBL18997885 | 0.77 | PDK2 (0.50) | BACE1PDCD1CD274TACR1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016152-A1 | Process for the preparation of 4`-haloalkylbiphenyl-2-carboxylic acids | SALTIGO GMBH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016152-A1 | Process for the preparation of 4`-haloalkylbiphenyl-2-carboxylic acids | CYP4B1, HACL2, UGT1A4 | BACE1 4371/4885PTGDR2 2948/4885PDCD1 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.