SCHEMBL3439664

SCHEMBL3439664

Cc1ccc(OC2CCC(C3CCC(C)CC3)CC2)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYK P43405 1/20 0.41
MCHR1 Q99705 2/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
GRIK1 P39086 2/20 0.37
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
SLC6A4 P31645 3/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
GRIA2 P42262 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP2D6 P10635 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A3 Q01959 1/20 0.34
GRM2 Q14416 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TAS1R2 Q8TE23 1/20 0.33
RORC P51449 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18027648 0.87 LMNA (0.42) SYKTSHRGRIK1LMNAHPGD
SCHEMBL1688861 0.83 S1PR5 (0.39) SYKTSHRGRIK1LMNAHPGD
SCHEMBL24044010 0.80 KDM4E (0.46) SYKMCHR1LMNAHPGDSMN1; SMN2
SCHEMBL10196348 0.79 ACHE (0.55) SYKMCHR1TSHRMAPK1HPGD
SCHEMBL3439658 0.77 SYK (0.41) SYKMCHR1LMNAHPGDSLC6A4
SCHEMBL16922991 0.77 MCHR1 (0.38) SYKMCHR1SLC6A4SLC6A2SLC6A3
SCHEMBL171093 0.77 HTR2C (0.47) SYKSLC6A4HTR2CHTR2BSLC6A2
SCHEMBL19557076 0.76 FPR2 (0.41) MCHR1SMN1; SMN2
SCHEMBL5544941 0.75 HTR2C (0.49) SYKHTR2CHTR2BSMN1; SMN2CYP2D6
SCHEMBL16270599 0.75 S1PR5 (0.45) SYKSLC6A4HTR2CSMN1; SMN2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901353-B2 Polyimide precursor, polyimide, and liquid crystal aligning agent NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-12-02 US disclosed
US-8829153-B2 Polyimide precursor composition containing polyamic acid alkyl ester NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-09-09 US disclosed
US-20120101236-A1 POLYIMIDE PRECURSOR COMPOSITION CONTAINING POLYAMIC ACID ALKYL ESTER NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-04-26 US disclosed