Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25701678 | 0.85 | HTR2A (0.41) | HRH3TAAR1L3MBTL1LMNAKCNH2 | |
| SCHEMBL3059072 | 0.81 | HRH3 (0.70) | HRH3TAAR1CHRNA7KCNH2 | |
| SCHEMBL9180552 | 0.80 | LMNA (0.52) | HRH3L3MBTL1LMNA | |
| SCHEMBL18762839 | 0.80 | HRH3 (0.84) | HRH3TAAR1CHRNA7KCNH2SIGMAR1 | |
| SCHEMBL23134289 | 0.79 | HRH3 (0.54) | HRH3TAAR1LMNASIGMAR1 | |
| SCHEMBL3440215 | 0.79 | HRH3 (0.61) | HRH3TAAR1CHRNA7KCNH2 | |
| SCHEMBL26408111 | 0.79 | SIGMAR1 (0.40) | HRH3TAAR1L3MBTL1LMNAKCNH2 | |
| SCHEMBL25701595 | 0.77 | SIGMAR1 (0.54) | HRH3SIGMAR1 | |
| SCHEMBL3057063 | 0.76 | HRH3 (0.70) | HRH3TAAR1CHRNA7KCNH2SIGMAR1 | |
| SCHEMBL15242107 | 0.76 | HRH3 (0.58) | HRH3TAAR1CHRNA7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402329-A1 | Analgetic phenylsulphonamides | Boehringer Ingelheim International GmbH (DE) | 2012-01-04 | — | — | EP | disclosed |
| EP-2284166-A1 | Arylsulfonamides with analgetic activity | Boehringer Ingelheim International GmbH (DE) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009021758-A1 | ARYLSULFONAMIDES HAVING AN ANALGESIC EFFECT | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009021946-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| WO-2008022945-A1 | ARYL SULFONAMIDES WITH AN ANALGESIC ACTION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-28 | — | — | WO | disclosed |