Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.45 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.40 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.40 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL995723 | 0.79 | CKS1B (0.42) | PTPN1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14980073 | 0.79 | PTPN1 (0.39) | PTPN1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3440628 | 0.77 | PTPN1 (0.37) | PTPN1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL995100 | 0.74 | CD274 (0.47) | — | |
| SCHEMBL29955292 | 0.73 | ENPP2 (0.55) | ENPP2ORAI1ORAI2ORAI3MTNR1A | |
| SCHEMBL3440653 | 0.72 | AOC3 (0.40) | MTNR1AMTNR1BMEN1KMT2APKM | |
| SCHEMBL3471030 | 0.72 | PTPN1 (0.36) | PTPN1MEN1KMT2AALDH1A1CA1 | |
| SCHEMBL10126440 | 0.70 | ABL1 (0.43) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29952130 | 0.70 | POLB (0.55) | MEN1KMT2AALDH1A1RAB9APKM | |
| SCHEMBL134254 | 0.70 | POLB (0.55) | MEN1KMT2AALDH1A1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331418-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | UNIVERSITY OF DELAWARE | 2010-12-30 | — | — | US | disclosed |
| US-7807713-B2 | Pan-antagonists for the androgen receptor and androgen associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2010-10-05 | — | — | US | disclosed |
| US-7807713-B2 | Pan-antagonists for the androgen receptor and androgen associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090270512-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-29 | — | — | US | disclosed |
| US-20090270512-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-29 | — | — | US | disclosed |
| US-7550505-B2 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550505-B2 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080064757-A1 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-03-13 | — | — | US | disclosed |
| WO-2008013791-A2 | PAN-ANTAGONISTS FOR THE ANDROGEN RECEPTOR AND ANDROGEN RECEPTOR MUTANTS ASSOCIATED WITH ANTI-ANDROGEN WITHDRAWAL | UNIVERSITY OF DELAWARE (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270512-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | AR, NR5A1, SHBG | ENPP2 498/4885ORAI1 4392/4885ORAI2 4706/4885 |
| US-20080064757-A1 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | AR, NR5A1, SHBG | ENPP2 498/4885ORAI1 4392/4885ORAI2 4706/4885 |
| US-20100331418-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | AR, NR5A1, SHBG | ENPP2 498/4885ORAI1 4392/4885ORAI2 4706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.