Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8756705 | 0.78 | AOC3 (0.49) | AOC3ADRA2AADRA1AL3MBTL1PKM | |
| SCHEMBL3440588 | 0.72 | ENPP2 (0.45) | PKMMTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL995723 | 0.72 | CKS1B (0.42) | L3MBTL1MEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14980073 | 0.72 | PTPN1 (0.39) | MEN1CYP1A2KMT2A | |
| SCHEMBL18552988 | 0.71 | CNR2 (0.44) | AOC3L3MBTL1PKMCASRMEN1 | |
| SCHEMBL6866452 | 0.70 | AOC3 (0.47) | AOC3L3MBTL1PKMCHRM2CHRM1 | |
| SCHEMBL2093768 | 0.70 | AOC3 (0.59) | AOC3L3MBTL1PKMCHRM2CHRM1 | |
| SCHEMBL3440628 | 0.70 | PTPN1 (0.37) | PKMMTNR1AMTNR1BMEN1CYP1A2 | |
| SCHEMBL4824457 | 0.69 | BRD4 (0.47) | ADRA2AADRA1AL3MBTL1CHRM2CHRM1 | |
| SCHEMBL995100 | 0.69 | CD274 (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807713-B2 | Pan-antagonists for the androgen receptor and androgen associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090270512-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-10-29 | — | — | US | disclosed |
| US-7550505-B2 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | UNIVERSITY OF DELAWARE (US) | 2009-06-23 | — | — | US | disclosed |
| US-20080064757-A1 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-03-13 | — | — | US | disclosed |
| WO-2008013791-A2 | PAN-ANTAGONISTS FOR THE ANDROGEN RECEPTOR AND ANDROGEN RECEPTOR MUTANTS ASSOCIATED WITH ANTI-ANDROGEN WITHDRAWAL | UNIVERSITY OF DELAWARE (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270512-A1 | Pan-Antagonists For The Androgen Receptor And Androgen Receptor Mutants Associated With Anti-Androgen Withdrawal | AR, NR5A1, SHBG | AOC3 4334/4885ADRA2A 53/4885ADRA1A 57/4885 |
| US-20080064757-A1 | Pan-antagonists for the androgen receptor and androgen receptor mutants associated with anti-androgen withdrawal | AR, NR5A1, SHBG | AOC3 4334/4885ADRA2A 53/4885ADRA1A 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.