Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 5/20 | 0.84 |
| ▸ | DRD2 | P14416 | 3/20 | 0.84 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.84 |
| ▸ | HTR3B | O95264 | 3/20 | 0.84 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.84 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.84 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.84 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.84 |
| ▸ | DRD3 | P35462 | 2/20 | 0.84 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.84 |
| ▸ | HTR6 | P50406 | 1/20 | 0.84 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | MAPT | P10636 | 1/20 | 0.82 |
| ▸ | HTR7 | P34969 | 5/20 | 0.66 |
| ▸ | HTR1A | P08908 | 5/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6366499 | 0.92 | HTR3A (1.00) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| SCHEMBL379 | 0.92 | HTR3A (1.00) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| SCHEMBL29396943 | 0.92 | HTR3A (1.00) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| Piperazine SCHEMBL28843777 | 0.90 | HTR3A (0.96) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL6602545 | 0.90 | LMNA (1.00) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| Bromide SCHEMBL27797305 | 0.90 | HTR3A (0.96) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL246416 | 0.90 | LMNA (1.00) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL29397565 | 0.90 | LMNA (1.00) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| Hydrochloric Acid SCHEMBL9069817 | 0.89 | HTR3A (0.93) | HTR3ADRD2HTR3EHTR3BADRB1 | |
| Iodide SCHEMBL27505006 | 0.89 | HTR3A (0.93) | HTR3ADRD2HTR3EHTR3BADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807712-B2 | Oxy substituted chalcones as antihyperglycemic and antidyslipidemic agents | PRATAP RAM | 2010-10-05 | — | — | US | claimed |