SCHEMBL3440755

SCHEMBL3440755

CC(CC=CC#N)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.44
AOC3 Q16853 2/20 0.40
TRPA1 O75762 5/20 0.39
RIPK1 Q13546 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.35
HTR2A P28223 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6987947 0.79 LMNA (0.37) TAAR1AOC3TRPA1TSHR
SCHEMBL6987943 0.79 LMNA (0.37) TAAR1AOC3TRPA1TSHR
SCHEMBL5852562 0.76 TAAR1 (0.50) TAAR1AOC3TRPA1RIPK1HTR2A
SCHEMBL5852566 0.76 TAAR1 (0.50) TAAR1AOC3TRPA1RIPK1HTR2A
SCHEMBL996150 0.75 TRPA1 (0.31) TRPA1TSHR
SCHEMBL996151 0.75 TRPA1 (0.31) TRPA1TSHR
SCHEMBL10644871 0.75 TAAR1 (0.48) TAAR1AOC3TRPA1RIPK1HTR2A
SCHEMBL6014403 0.75 TAAR1 (0.54) TAAR1AOC3TRPA1RIPK1HTR2A
SCHEMBL6014399 0.75 TAAR1 (0.54) TAAR1AOC3TRPA1RIPK1HTR2A
SCHEMBL10644867 0.75 TAAR1 (0.48) TAAR1AOC3TRPA1RIPK1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2069468-B1 PERFUME DISPENSING SYSTEM HENKEL AG & CO KGAA (DE) 2012-12-26 EP disclosed
US-7807616-B2 Geranonitrile substitute HENKEL AG & CO. KGAA (DE) 2010-10-05 US disclosed
US-20070265183-A1 fragrance mixture for laundering, care and/or cleaning component; producing a citrus odor; 3,7-dimethyloct-6-enenitrile mixtures; stability; nontoxic HENKEL AG & CO. KGAA (DE) 2007-11-15 US disclosed