SCHEMBL344081

SCHEMBL344081

CCC(CO)Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.53
IDO1 P14902 4/20 0.42
TSHR P16473 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SIGMAR1 Q99720 4/20 0.39
IGF1R P08069 1/20 0.39
ALOX15 P16050 1/20 0.39
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
TACR1 P25103 1/20 0.37
DPP4 P27487 1/20 0.37
DPP7 Q9UHL4 1/20 0.37
FDPS P14324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14433237 0.81 PNMT (0.56) PNMTIDO1TSHRTAAR1SIGMAR1
SCHEMBL344690 0.79 SLC6A2 (0.48) IDO1SLC6A2SLC6A4SLC6A3
SCHEMBL14402442 0.78 PNMT (0.56) PNMTIDO1TSHRTAAR1SMN1; SMN2
SCHEMBL7376268 0.78 PNMT (0.61) PNMTIDO1TSHRTAAR1SIGMAR1
SCHEMBL346225 0.77 PNMT (0.56) PNMTIDO1TSHRTAAR1
SCHEMBL9120036 0.76 CA2 (0.49) PNMTTSHRIGF1RALOX15SLC6A2
SCHEMBL345251 0.76 PSMB5 (0.38) SMN1; SMN2
SCHEMBL13165986 0.76 PNMT (0.63) PNMTIDO1TSHRTAAR1SMN1; SMN2
SCHEMBL13165985 0.76 PNMT (0.63) PNMTIDO1TSHRTAAR1SMN1; SMN2
SCHEMBL19772459 0.76 PNMT (0.63) PNMTIDO1TSHRTAAR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210069071-A1 COSMETIC SOAP GEL STICKS WITH IMPROVED MANUFACTURABILITY HENKEL AG & CO. KGAA (DE) 2021-03-11 US claimed
EP-2453867-A2 COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT Henkel AG & Co. KGaA (DE) 2012-05-23 EP claimed
EP-2349185-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY Henkel AG & Co. KGaA (DE) 2011-08-03 EP claimed
EP-2349184-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL Henkel AG & Co. KGaA (DE) 2011-08-03 EP claimed
WO-2011006689-A2 COSMETIC AND DERMATOLOGICAL TOPICAL COMPOSITIONS HAVING A HAIR GROWTH-MINIMISING OR HAIR GROWTH-INHIBITING EFFECT HENKEL AG & CO. KGAA (DE) 2011-01-20 WO claimed
WO-2010009976-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL HENKEL AG & CO. KGAA (DE) 2010-01-28 WO claimed
WO-2010009977-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY HENKEL AG & CO. KGAA (DE) 2010-01-28 WO claimed
US-11504309-B2 Deo emulsion for aerosols, deodorant comprising the same and use of the deodorant HENKEL AG & CO. KGAA (DE) 2022-11-22 US disclosed
US-11324675-B2 Deo emulsion for aerosols with reduced stain problem, deodorant comprising the same and use of the deodorant HENKEL AG & CO. KGAA (DE) 2022-05-10 US disclosed
US-11045399-B2 Residue-minimized antiperspirant composition with improved skin feel HENKEL AG & CO. KGAA (DE) 2021-06-29 US disclosed
US-20210093520-A1 DEO EMULSION FOR AEROSOLS, DEODORANT COMPRISING THE SAME AND USE OF THE DEODORANT HENKEL AG & CO. KGAA (DE) 2021-04-01 US disclosed
US-20210093522-A1 DEO EMULSION FOR AEROSOLS WITH REDUCED STAIN PROBLEM, DEODORANT COMPRISING THE SAME AND USE OF THE DEODORANT HENKEL AG & CO. KGAA (DE) 2021-04-01 US disclosed
US-20210069071-A1 COSMETIC SOAP GEL STICKS WITH IMPROVED MANUFACTURABILITY HENKEL AG & CO. KGAA (DE) 2021-03-11 US disclosed
EP-2167017-A2 COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION HAVING A HYDROGEL FORMER Henkel AG & Co. KGaA (DE) 2010-03-31 EP disclosed
WO-2010031657-A2 USE OF UREA DERIVATIVES AND PHENACYLTHIAZOLIUM SALTS FOR THE TREATMENT OF BODY ODOUR HENKEL AG & CO. KGAA (DE) 2010-03-25 WO disclosed
WO-2010009976-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A NON-AEROSOL HENKEL AG & CO. KGAA (DE) 2010-01-28 WO disclosed
WO-2010009977-A2 MORE EFFECTIVE ANHYDROUS DEODORANT COMPOSITIONS APPLIED AS A SPRAY HENKEL AG & CO. KGAA (DE) 2010-01-28 WO disclosed
WO-2009083547-A2 WATER-FREE ANTIPERSPIRANT SPRAYS WITH IMPROVED SUBSTANCE RELEASE HENKEL AG & CO. KGAA (DE) 2009-07-09 WO disclosed
WO-2008155382-A2 COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION HAVING A HYDROGEL FORMER HENKEL AG & CO. KGAA (DE) 2008-12-24 WO disclosed
WO-2008155391-A2 COSMETIC STICK BASED ON A CONGEALED OIL-IN-WATER DISPERSION/EMULSION HENKEL AG & CO. KGAA (DE) 2008-12-24 WO disclosed