Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22115841 | 0.94 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL3440898 | 0.89 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL7761501 | 0.87 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL16537305 | 0.85 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL16286804 | 0.85 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL107693 | 0.84 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL22367588 | 0.84 | HCAR2 (0.53) | TSHRHPGDHCAR2ATMNAAA | |
| SCHEMBL22607678 | 0.84 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL21218910 | 0.84 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL9442075 | 0.84 | TSHR (0.84) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4725470-A1 | CURABLE DENTAL COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2026-04-15 | — | — | EP | disclosed |
| US-20250032366-A1 | DENTAL CURABLE COMPOSITION | KURARAY NORITAKE DENTAL INC. (JP) | 2025-01-30 | — | — | US | disclosed |
| US-20250009607-A1 | DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE | KURARAY NORITAKE DENTAL INC. (JP) | 2025-01-09 | — | — | US | disclosed |
| WO-2024253204-A1 | CURABLE DENTAL COMPOSITION | クラレノリタケデンタル株式会社 | 2024-12-12 | — | — | WO | disclosed |
| EP-4464301-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | Kuraray Noritake Dental Inc. (JP) | 2024-11-20 | — | — | EP | disclosed |
| EP-4445891-A1 | DENTAL CURABLE COMPOSITION | Kuraray Noritake Dental Inc. (JP) | 2024-10-16 | — | — | EP | disclosed |
| CN-118338879-A | Curable composition for dental use | 可乐丽则武齿科株式会社 | 2024-07-12 | — | — | CN | disclosed |
| WO-2023136337-A1 | DENTAL COMPOSITION, METHOD FOR MANUFACTURING SAME, AND DENTAL SURFACE-TREATED FILLER | クラレノリタケデンタル株式会社 | 2023-07-20 | — | — | WO | disclosed |
| WO-2023106419-A1 | DENTAL CURABLE COMPOSITION | クラレノリタケデンタル株式会社 | 2023-06-15 | — | — | WO | disclosed |
| US-11607370-B2 | Dental composition | KURARAY NORITAKE DENTAL INC. (JP) | 2023-03-21 | — | — | US | disclosed |
| CN-111225647-B | Dental composition | 可乐丽则武齿科株式会社 | 2023-02-28 | — | — | CN | disclosed |
| WO-2022210010-A1 | DENTAL PRETREATMENT AGENT | サンメディカル株式会社 | 2022-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11607370-B2 | Dental composition | ITGAL, ITGA1, ITGB3 | TSHR 4827/4885HPGD 3003/4885ALDH1A1 1948/4885 |
| US-20250032366-A1 | DENTAL CURABLE COMPOSITION | H1-0, COL1A1, CHAF1B | TSHR 4352/4885HPGD 2520/4885ALDH1A1 1530/4885 |
| US-20250009607-A1 | DENTAL COMPOSITION AND METHOD OF PRODUCTION THEREOF, AND SURFACE-TREATED FILLER FOR DENTAL USE | CAD, SEM1, CAPZA1 | TSHR 3083/4885HPGD 1522/4885ALDH1A1 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.