Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 6/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3609382 | 0.93 | FBP1 (0.48) | FBP1PDE3BPDE3AABCB11MAOA | |
| Hydrochloric Acid SCHEMBL3440981 | 0.92 | FBP1 (0.47) | FBP1PDE3BPDE3AABCB11MAOA | |
| SCHEMBL3440867 | 0.85 | FBP1 (0.56) | FBP1PDE3BPDE3AABCB11MAOA | |
| SCHEMBL3440893 | 0.82 | FBP1 (0.59) | FBP1PDE3BPDE3AABCB11MAOA | |
| SCHEMBL3440914 | 0.78 | FBP1 (0.48) | FBP1PDE3BPDE3AABCB11MAOA | |
| SCHEMBL3440983 | 0.77 | FBP1 (0.66) | FBP1PDE3BPDE3AABCB11MAOA | |
| Hydrochloric Acid SCHEMBL3618780 | 0.77 | FBP1 (0.47) | FBP1PDE3BPDE3AABCB11MAOA | |
| SCHEMBL3614084 | 0.77 | FBP1 (0.55) | FBP1PDE3BPDE3AABCB11MAOA | |
| SCHEMBL3440936 | 0.76 | FBP1 (0.48) | FBP1PDE3BPDE3AABCB11MAOA | |
| SCHEMBL3440912 | 0.74 | FBP1 (0.50) | FBP1PDE3BPDE3AABCB11MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229385-A2 | BENZIMIDAZOLEDIHYDROTHIADIAZINONE DERIVATIVES AS FRUCTOSE-1,6-BISPHOSPHATASE INHIBITORS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | Merck Patent GmbH (DE) | 2010-09-22 | — | — | EP | claimed |
| WO-2009062576-A2 | BENZIMIDAZOLEDIHYDROTHIADIAZINONE DERIVATIVES AS FRUCTOSE-1,6-BISPHOSPHATASE INHIBITORS, AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2009-05-22 | — | — | WO | claimed |