SCHEMBL344115

SCHEMBL344115

Nc1ccc(S(N)(=O)=O)cc1C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.63
KMT2A Q03164 3/20 0.63
MEN1 O00255 2/20 0.63
MAPT P10636 2/20 0.63
PKM P14618 2/20 0.63
GAA P10253 1/20 0.63
RAB9A P51151 1/20 0.63
GFER P55789 1/20 0.57
RXFP1 Q9HBX9 1/20 0.57
CA2 P00918 9/20 0.55
CA12 O43570 7/20 0.55
CA1 P00915 7/20 0.55
CA9 Q16790 7/20 0.55
CA14 Q9ULX7 6/20 0.55
CA6 P23280 5/20 0.55
CA5A P35218 5/20 0.55
CA7 P43166 5/20 0.55
CA5B Q9Y2D0 5/20 0.55
CA4 P22748 4/20 0.55
USP2 O75604 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL715377 0.86 KDM4E (0.59) KDM4EKMT2AMEN1MAPTPKM
SCHEMBL342600 0.85 ALDH1A1 (0.62) KDM4EKMT2AMEN1MAPTPKM
SCHEMBL1805819 0.85 KDM4E (0.63) KDM4EKMT2AMEN1MAPTPKM
SCHEMBL1462829 0.85 CA2 (0.60) KDM4EKMT2AMEN1MAPTPKM
SCHEMBL7824801 0.84 CA2 (0.55) KDM4EKMT2AMEN1MAPTPKM
SCHEMBL11121477 0.83 KDM4E (0.61) KDM4EKMT2AMEN1MAPTPKM
SCHEMBL2512589 0.83 LMNA (0.64) KDM4EKMT2AMEN1MAPTPKM
SCHEMBL3527141 0.82 ALDH1A1 (0.70) KDM4EKMT2AMEN1MAPTPKM
Ethane SCHEMBL27571371 0.81 ALDH1A1 (0.59) KDM4EKMT2AMEN1MAPTPKM
SCHEMBL16790377 0.81 HSD17B10 (0.59) KDM4EKMT2AMEN1MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4001284-A PRIMARY AMINES, 2,4-DIPHENOXY-5-SULFAMOYLBENZOIC ACID HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-04 US claimed
CN-107012695-B Penetrating fluid for ink jet textile printing, ink jet textile printing method, and ink jet textile printing apparatus 精工爱普生株式会社 2020-08-07 CN disclosed
EP-3199603-B1 INK JET PRINTING PENETRANT, INK JET PRINTING METHOD, AND INK JET PRINTING APPARATUS SEIKO EPSON CORP (JP) 2020-04-15 EP disclosed
EP-3354640-A2 MIF INHIBITORS AND THEIR USES Innovimmune Biotherapeutics, Inc. (US) 2018-08-01 EP disclosed
CN-105602279-B Tetraazatetradecane porphyrin pigment, printing ink composition, recording method and tingle body 日本化药株式会社 2018-06-15 CN disclosed
EP-2696682-B1 MIF INHIBITORS AND THEIR USES INNOVIMMUNE BIOTHERAPEUTICS INC (US) 2018-03-21 EP disclosed
EP-2441806-B1 PORPHYRAZINE COLORING MATTER, INK COMPOSITION, RECORDING METHOD, AND COLORED OBJECT NIPPON KAYAKU KK (JP) 2017-09-06 EP disclosed
CN-107012695-A Ink-jet cloth printing penetrating fluid, ink jet printing method and ink-jet printing device 精工爱普生株式会社 2017-08-04 CN disclosed
US-20170218214-A1 INK JET PRINTING PENETRANT, INK JET PRINTING METHOD, AND INK JET PRINTING APPARATUS SEIKO EPSON CORPORATION (JP) 2017-08-03 US disclosed
EP-3199603-A1 INK JET PRINTING PENETRANT, INK JET PRINTING METHOD, AND INK JET PRINTING APPARATUS Seiko Epson Corporation (JP) 2017-08-02 EP disclosed
US-4847365-A POLYAMIDES, POLYESTERS, OLEFIN POLYMERS CIBA-GEIGY CORPORATION (US) 1989-07-11 US disclosed
US-4673631-A OF AN AMINO ACID COMPOUND CANON KABUSHIKI KAISHA (JP) 1987-06-16 US disclosed
EP-0183651-A2 Metal complexes, process for their preparation and their use CIBA-GEIGY AG (CH) 1986-06-04 EP disclosed
EP-0008072-B1 SUBSTITUTED ANTHRANILIC ACID AMIDES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1984-02-22 EP disclosed
US-4406895-A Base-substituted anthranilic acids, a process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1983-09-27 US disclosed
US-4311641-A Chromium complexes of mixed azo compounds CIBA-GEIGY CORPORATION (US) 1982-01-19 US disclosed
US-4001284-A PRIMARY AMINES, 2,4-DIPHENOXY-5-SULFAMOYLBENZOIC ACID HOECHST AKTIENGESELLSCHAFT (DT) 1977-01-04 US disclosed
US-3969302-A Process for the dyeing of colored shaped articles of high polymer, synthetic resins and preparations for such process CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3933802-A New sulphamoylbenzoic acid amides CIBA-GEIGY CORPORATION (US) 1976-01-20 US disclosed
US-3879402-A Process for preparing 2-chloro-5-sulfamoylbenzoic acids PFIZER 1975-04-22 US disclosed