SCHEMBL3441242

SCHEMBL3441242

O=C(c1ccc(F)cc1)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)c1ccc(F)cc1

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.52
CES2 O00748 1/20 0.52
CA2 P00918 3/20 0.48
CA1 P00915 2/20 0.48
PLOD2 O00469 1/20 0.47
BCL2L1 Q07817 1/20 0.45
BAD Q92934 1/20 0.45
PTPN1 P18031 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
LTA4H P09960 1/20 0.42
CYP1A1 P04798 1/20 0.40
CYP1B1 Q16678 1/20 0.40
TNFRSF1A P19438 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
KCNN4 O15554 1/20 0.39
HTR7 P34969 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1272402 0.86 CES1 (0.52) CES1CES2CA2CA1PLOD2
SCHEMBL16823 0.81 CES1 (0.62) CES1CES2CA2CA1PLOD2
SCHEMBL29035937 0.79 CES1 (0.54) CES1CES2CA2CA1PLOD2
SCHEMBL7804393 0.77 CES1 (0.52) CES1CES2CA2CA1PLOD2
SCHEMBL28356730 0.77 CES1 (0.52) CES1CES2CA2CA1PLOD2
SCHEMBL31507803 0.77 CES1 (0.46) CES1CES2CA2CA1PLOD2
SCHEMBL22874628 0.76 CES2 (0.56) CES1CES2CA2CA1PLOD2
SCHEMBL9859948 0.76 CES1 (0.50) CES1CES2CA2CA1PLOD2
SCHEMBL5698489 0.76 CES1 (0.50) CES1CES2CA2CA1PLOD2
SCHEMBL10831883 0.76 CES2 (0.50) CES1CES2CA2CA1PLOD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8344091-B2 Polymer and membrane-electrode assembly for fuel cell, and fuel cell system including the same SAMSUNG SDI CO. LTD. (KR) 2013-01-01 US disclosed
EP-2128185-B1 Polymer and membrane-electrode assembly for fuel cell, and fuel cell system including the same SAMSUNG SDI CO LTD (KR) 2010-09-15 EP disclosed
EP-2128185-A1 Polymer and membrane-electrode assembly for fuel cell, and fuel cell system including the same Samsung SDI Co., Ltd. (KR) 2009-12-02 EP disclosed
US-20090280384-A1 Polymer and membrane-electrode assembly for fuel cell, and fuel cell system including the same SAMSUNG SDI CO., LTD., A CORPORATION CHARTERED IN AND EXISTING UNDET THE LAWS OF THE REPUBLIC OF KOREA (KR) 2009-11-12 US disclosed