SCHEMBL7804393

SCHEMBL7804393

CC(F)(F)C(=O)c1ccc(F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.52
CES2 O00748 1/20 0.52
CA2 P00918 3/20 0.48
CA1 P00915 2/20 0.48
PLOD2 O00469 1/20 0.47
BCL2L1 Q07817 1/20 0.45
BAD Q92934 1/20 0.45
ABCC9 O60706 1/20 0.45
ABCC8 Q09428 1/20 0.45
KCNJ11 Q14654 1/20 0.45
KCNJ8 Q15842 1/20 0.45
PTPN1 P18031 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
HTR7 P34969 1/20 0.42
MAPT P10636 1/20 0.42
LTA4H P09960 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
MLYCD O95822 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5698489 0.84 CES1 (0.50) CES1CES2CA2CA1PLOD2
SCHEMBL9859948 0.84 CES1 (0.50) CES1CES2CA2CA1PLOD2
SCHEMBL2625487 0.84 CES2 (0.54) CES1CES2CA2CA1PLOD2
SCHEMBL15851476 0.82 CA2 (0.64) CES1CES2CA2NPC1RAB9A
SCHEMBL5466629 0.82 CES2 (0.52) CES1CES2CA2CA1PLOD2
SCHEMBL2696027 0.82 CES2 (0.52) CES1CES2CA2CA1PLOD2
SCHEMBL16823 0.81 CES1 (0.62) CES1CES2CA2CA1PLOD2
SCHEMBL5476352 0.81 ABCC9 (0.57) CES1CES2CA2CA1PLOD2
SCHEMBL29043915 0.80 CES2 (0.50) CES1CES2CA2CA1PLOD2
SCHEMBL7798781 0.80 CES2 (0.61) CES1CES2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed
EP-0780380-B1 Triazole derivatives with antimycotic action and intermediates SS PHARMACEUTICAL CO (JP) 2001-06-13 EP disclosed
US-6002028-A FUNGICIDES SS PHARMACEUTICAL CO., LTD. (JP) 1999-12-14 US disclosed
US-5986144-A Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient SS PHARMACEUTICAL CO., LTD. (JP) 1999-11-16 US disclosed
US-5945438-A ANTIMYCOTIC AGENT SS PHARMACEUTICAL CO., LTD. (JP) 1999-08-31 US disclosed
EP-0780380-A1 Triazole derivatives with antimycotic action and intermediates SS PHARMACEUTICAL CO., LTD. (JP) 1997-06-25 EP disclosed