Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804393 | 0.84 | CES1 (0.52) | CES1CES2CA2CA1PLOD2 | |
| SCHEMBL9859948 | 0.83 | CES1 (0.50) | CES1CES2CA2CA1PLOD2 | |
| SCHEMBL2625487 | 0.82 | CES2 (0.54) | CES1CES2CA2CA1PLOD2 | |
| SCHEMBL7991415 | 0.80 | CA2 (0.59) | CES1CES2CA2NPC1RAB9A | |
| SCHEMBL9115535 | 0.80 | LMNA (0.44) | CA2NPC1RAB9AMAPTCYP1A2 | |
| SCHEMBL2696027 | 0.80 | CES2 (0.52) | CES1CES2CA2CA1PLOD2 | |
| SCHEMBL5466629 | 0.80 | CES2 (0.52) | CES1CES2CA2CA1PLOD2 | |
| SCHEMBL16823 | 0.79 | CES1 (0.62) | CES1CES2CA2CA1PLOD2 | |
| SCHEMBL5476352 | 0.79 | ABCC9 (0.57) | CES1CES2CA2CA1PLOD2 | |
| SCHEMBL29043915 | 0.78 | CES2 (0.50) | CES1CES2CA2CA1PLOD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1297022-B1 | NOVEL PHOTOINITIATORS | KIMBERLY CLARK CO (US) | 2006-07-19 | — | — | EP | disclosed |
| EP-1297022-A1 | NOVEL PHOTOINITIATORS AND APPLICATIONS THEREFOR | Kimberly-Clark Worldwide, Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| US-6486227-B2 | FOR USE IN GENERATING A REACTIVE SPECIES POLYMERIZING POLYMERIZABLE MATERIALS, FOR CURING UNSATURATED OLIGOMER/MONOMER MIXTURE, AND LAMINATING USING PHOTOINITIATORS, FOR INKS, ADHESIVES | KIMBERLY-CLARK WORLDWIDE, INC. | 2002-11-26 | — | — | US | disclosed |
| US-20020099111-A1 | Novel photoinitiators and applications therefor | MIND FUSION, LLC | 2002-07-25 | — | — | US | disclosed |
| WO-2002000735-A1 | NOVEL PHOTOINITIATORS AND APPLICATIONS THEREFOR | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099111-A1 | Novel photoinitiators and applications therefor | ARL1, VCL, RAD54L | CES1 1547/4885CES2 2577/4885CA2 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.