Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13107652 | 0.91 | MAOB (0.42) | MAOBRAB9ACYP4F2CYP4A11PTGER4 | |
| SCHEMBL3442852 | 0.88 | MAOB (0.50) | MAOBCYP4F2CYP4A11PTGER4CYP19A1 | |
| SCHEMBL3442492 | 0.87 | RAB9A (0.41) | MAOBRAB9ACYP4F2CYP4A11PTGER4 | |
| SCHEMBL3442487 | 0.85 | MAOB (0.46) | MAOBRAB9ACYP4F2CYP4A11PTGER4 | |
| SCHEMBL3442976 | 0.85 | RAB9A (0.46) | MAOBRAB9ACYP4F2CYP4A11PTGER4 | |
| SCHEMBL3442779 | 0.84 | MAOB (0.45) | MAOBRAB9ACYP4F2CYP4A11PTGER4 | |
| SCHEMBL13123006 | 0.84 | RAB9A (0.45) | MAOBRAB9ACYP4F2CYP4A11PTGER4 | |
| SCHEMBL3442308 | 0.83 | CACNA1B (0.43) | MAOBMAPTNPSR1 | |
| SCHEMBL3442898 | 0.80 | GHSR (0.42) | PTGER4CYP3A4HRH3 | |
| SCHEMBL3443329 | 0.79 | F2 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812037-B2 | Dual antiplatelet/anticoagulant pyridoxine analogs | MEDICURE INTERNATIONAL, INC. (BB) | 2010-10-12 | — | — | US | disclosed |
| US-7812037-B2 | Dual antiplatelet/anticoagulant pyridoxine analogs | MEDICURE INTERNATIONAL, INC. (BB) | 2010-10-12 | — | — | US | disclosed |
| EP-1817288-A4 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | MEDICURE INT INC (BB) | 2009-08-26 | — | — | EP | disclosed |
| EP-1817288-A1 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | Medicure International Inc. (BB) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006050598-A1 | DUAL ANTIPLATELET/ANTICOAGULANT PYRIDOXINE ANALOGS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-18 | — | — | WO | disclosed |
| US-20060094761-A1 | Dual antiplatelet/anticoagulant pyridoxine analogs | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094761-A1 | Dual antiplatelet/anticoagulant pyridoxine analogs | PNPO, PLPBP, PRDX6 | MAOB 260/4885RAB9A 3065/4885CYP4F2 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.