SCHEMBL3445101

SCHEMBL3445101

Cc1cc(C)c(Cl)c(C(Cl)Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 14/20 0.41
CYP3A4 P08684 1/20 0.37
CHRM1 P11229 1/20 0.37
ALOX15 P16050 1/20 0.37
MAOA P21397 1/20 0.37
TBXA2R P21731 1/20 0.37
ADRA1A P35348 1/20 0.37
HTR2B P41595 1/20 0.37
FFAR4 Q5NUL3 1/20 0.32
HTT P42858 1/20 0.32
TSHR P16473 1/20 0.32
GPR35 Q9HC97 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17125221 0.81 LMNA (0.42) RAPGEF4CYP3A4CHRM1ALOX15MAOA
SCHEMBL234943 0.76 CYP3A4 (0.58) RAPGEF4CYP3A4CHRM1ALOX15MAOA
SCHEMBL2972493 0.73 CYP3A4 (0.55) RAPGEF4CYP3A4CHRM1ALOX15MAOA
SCHEMBL27561995 0.73 CYP3A4 (0.55) RAPGEF4CYP3A4CHRM1ALOX15MAOA
SCHEMBL1314635 0.73 CYP3A4 (0.55) RAPGEF4CYP3A4CHRM1ALOX15MAOA
SCHEMBL7901130 0.73 RAPGEF4 (0.36) RAPGEF4
SCHEMBL6454202 0.73 HPGD (0.36) RAPGEF4ALDH1A1MAPT
SCHEMBL19824105 0.71 RAPGEF4 (0.35) RAPGEF4CYP3A4CHRM1ALOX15MAOA
SCHEMBL7456754 0.70
SCHEMBL4960992 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4769396-A Process for the production of cellular organic silicate products BLOUNT DAVID H (US) 1988-09-06 US claimed
US-4695595-A Process for the production of cellular organic silicate products BLOUNT DAVID H 1987-09-22 US claimed
US-4346191-A Process for the production of amine polysulfide silicate reaction products and their reaction products BLOUNT DAVID H 1982-08-24 US claimed
US-4283311-A Process for the production of broken down cellulose copolymers BLOUNT DAVID H 1981-08-11 US claimed
EP-0025051-A1 PROCESS FOR THE PRODUCTION OF AN AQUEOUS DISPERSION OF POLY(ORGANIC-POLYSULFIDE-SILICATE)COPOLYMER BLOUNT, David H. (US) 1981-03-18 EP claimed
WO-1980001919-A1 PROCESS FOR THE PRODUCTION OF AN AQUEOUS DISPERSION OF POLY(ORGANIC-POLYSULFIDE-SILICATE)COPOLYMER BLOUNT D (US) 1980-09-18 WO claimed
US-4197229-A USED AS COATINGS, MOLDING MATERIALS, CAULKING COMPOUNDS BLOUNT DAVID H 1980-04-08 US claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
EP-2905349-B1 Ag ball, solder joint, formed solder, solder paste and silver paste SENJU METAL INDUSTRY CO (JP) 2017-05-17 EP disclosed
US-9266196-B2 Ag ball, ag core ball, flux-coated ag ball, flux-coated ag core ball, solder joint, formed solder, solder paste and ag paste SENJU METAL INDUSTRY CO., LTD. (JP) 2016-02-23 US disclosed
EP-2905349-A2 Ag ball, Ag core ball, flux-coated Ag ball, flux-coated Ag core ball, solder joint, formed solder, solder paste and Ag paste SENJU METAL INDUSTRY CO., LTD. (JP) 2015-08-12 EP disclosed
US-20150217409-A1 Ag BALL, Ag CORE BALL, FLUX-COATED Ag BALL, FLUX-COATED Ag CORE BALL, SOLDER JOINT, FORMED SOLDER, SOLDER PASTE AND Ag PASTE Senju Metal lndustry Co., Ltd. (JP) 2015-08-06 US disclosed
US-7816679-B2 Organic compound crystal and field-effect transistor SONY CORPORATION (JP) 2010-10-19 US disclosed
US-20090072227-A1 ORGANIC COMPOUND CRYSTAL AND FIELD-EFFECT TRANSISTOR UGAWA AKITO 2009-03-19 US disclosed
US-4283311-A Process for the production of broken down cellulose copolymers BLOUNT DAVID H 1981-08-11 US disclosed
US-4281110-A Process for the production of broken down lignin-cellulose silicate copolymers BLOUNT DAVID H 1981-07-28 US disclosed
EP-0025051-A1 PROCESS FOR THE PRODUCTION OF AN AQUEOUS DISPERSION OF POLY(ORGANIC-POLYSULFIDE-SILICATE)COPOLYMER BLOUNT, David H. (US) 1981-03-18 EP disclosed
WO-1980001919-A1 PROCESS FOR THE PRODUCTION OF AN AQUEOUS DISPERSION OF POLY(ORGANIC-POLYSULFIDE-SILICATE)COPOLYMER BLOUNT D (US) 1980-09-18 WO disclosed
US-4197229-A USED AS COATINGS, MOLDING MATERIALS, CAULKING COMPOUNDS BLOUNT DAVID H 1980-04-08 US disclosed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US disclosed