SCHEMBL7901130

SCHEMBL7901130

Cc1cc(C)c(B(c2c(C)cc(C)cc2C(Cl)Cl)c2c(C)cc(C)cc2C(Cl)Cl)c(C(Cl)Cl)c1

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7467085 0.88 RAPGEF4 (0.31) RAPGEF4
SCHEMBL8589371 0.84 FFAR4 (0.37)
SCHEMBL7456754 0.83
SCHEMBL1157695 0.75 RAPGEF4 (0.50) RAPGEF4
SCHEMBL9623685 0.73 RAPGEF4 (0.48) RAPGEF4
SCHEMBL3445101 0.73 RAPGEF4 (0.41) RAPGEF4
SCHEMBL6454202 0.70 HPGD (0.36) RAPGEF4
SCHEMBL7463587 0.67
SCHEMBL4960992 0.67
SCHEMBL30843789 0.66 RAPGEF4 (0.39) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6210863-B1 ORTHO-SUBSTITUTED ON AT LEAST TWO ARYL RADICALS, ADDITION POLYMERIZATION CIBA SPECIALTY CHEMICALS CORPORATION 2001-04-03 US disclosed
US-5952152-A POLYMERIZABLE MIXTURE COMPRISING AT LEAST ONE ETHYLENICALLY UNSATURATED COMPOUND AND AN ANIONIC BORON COMPOUND ACTIVATOR CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-09-14 US disclosed