SCHEMBL3445405

SCHEMBL3445405

C=Cc1ccccc1OCCCN(C)CC

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.44
HTR1B P28222 3/20 0.44
HTR1D P28221 2/20 0.44
ATM Q13315 1/20 0.43
ALDH1A1 P00352 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
HRH1 P35367 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3445006 0.86 ALDH1A1 (0.56) LMNAHTR1BHTR1DALDH1A1HPGD
SCHEMBL3446273 0.85 HTR1B (0.57) HTR1BALDH1A1HRH1
SCHEMBL3444957 0.81 HTR1B (0.55) HTR1BHTR1DALDH1A1
SCHEMBL3445823 0.81 HTR1B (0.48) HTR1BHTR1DALDH1A1
SCHEMBL3445434 0.81 ALDH1A1 (0.63) LMNAHTR1BHTR1DALDH1A1HPGD
SCHEMBL3445526 0.81 HTR1B (0.58) HTR1BALDH1A1HRH1
SCHEMBL3445440 0.80 ALDH1A1 (0.66) HTR1BHTR1DALDH1A1
SCHEMBL3445531 0.80 ALDH1A1 (0.66) HTR1BHTR1DALDH1A1
SCHEMBL406835 0.80 CYP1A2 (0.56) LMNAHTR1BALDH1A1L3MBTL1HPGD
SCHEMBL3446080 0.79 HTR1B (0.56) HTR1BALDH1A1HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed