SCHEMBL3445650

SCHEMBL3445650

C=Cc1ccccc1OCCCCCN(C)C

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR1B P28222 2/20 0.56
KDM4E B2RXH2 3/20 0.51
HRH1 P35367 1/20 0.48
HTR7 P34969 1/20 0.46
ALDH1A1 P00352 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3446080 1.00 HTR1B (0.56) HTR1BKDM4EHRH1HTR7ALDH1A1
SCHEMBL3445526 0.98 HTR1B (0.58) HTR1BKDM4EHRH1HTR7ALDH1A1
SCHEMBL3446273 0.93 HTR1B (0.57) HTR1BKDM4EHRH1HTR7ALDH1A1
SCHEMBL3793697 0.86 ALDH1A1 (0.52) KDM4EALDH1A1
SCHEMBL3445531 0.84 ALDH1A1 (0.66) HTR1BALDH1A1
SCHEMBL3445440 0.84 ALDH1A1 (0.66) HTR1BALDH1A1
SCHEMBL19328405 0.84 ALDH1A1 (0.62) HTR1BKDM4EHRH1HTR7ALDH1A1
SCHEMBL3445442 0.84 ALDH1A1 (0.47) HTR1BKDM4EALDH1A1
SCHEMBL3445389 0.84 ALDH1A1 (0.47) HTR1BKDM4EALDH1A1
SCHEMBL3446377 0.83 ALDH1A1 (0.52) HTR1BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed