Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312529 | 0.85 | PTGS2 (0.58) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL347020 | 0.85 | PTGS2 (0.58) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL2839074 | 0.84 | CHRNA7 (0.53) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL5314124 | 0.81 | CHRNA7 (0.66) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL2466828 | 0.81 | CHRNA7 (0.66) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL2464195 | 0.81 | CHRNA7 (0.50) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL5309196 | 0.81 | CHRNA7 (0.66) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL347440 | 0.81 | CHRNA7 (0.66) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL2462524 | 0.81 | PTGS2 (0.60) | CHRNA7PTGS2PTGS1CA1CA2 | |
| SCHEMBL2633085 | 0.80 | PGR (0.41) | CHRNA7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444420-A1 | P-Cadherin antibodies | Pfizer Inc. (US) | 2012-04-25 | — | — | EP | disclosed |
| EP-2444419-A1 | P-Cadherin antibodies | Pfizer Inc. (US) | 2012-04-25 | — | — | EP | disclosed |