Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.30 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445658 | 0.80 | CHRNA7 (0.52) | LMNACHRNA7 | |
| SCHEMBL20207777 | 0.73 | NOS3 (0.45) | PGRALDH1A1LMNAPOLBRECQL | |
| SCHEMBL2212367 | 0.73 | NOS3 (0.45) | PGRALDH1A1LMNAPOLBRECQL | |
| SCHEMBL10211384 | 0.72 | MAPT (0.43) | ALDH1A1LMNAMAPT | |
| SCHEMBL12807984 | 0.65 | PTPN5 (0.47) | PGRALDH1A1PTPN5CHRNA7UGT2B7 | |
| SCHEMBL28483628 | 0.65 | PTPN5 (0.47) | PGRALDH1A1PTPN5CHRNA7UGT2B7 | |
| Acetic Acid SCHEMBL9711169 | 0.64 | NOS3 (0.42) | ALDH1A1LMNAPTPN5UGT2B7 | |
| SCHEMBL17916163 | 0.64 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL29861308 | 0.64 | PTPN5 (0.53) | PGRALDH1A1PTPN5UGT2B7 | |
| SCHEMBL7524578 | 0.64 | PTPN5 (0.53) | PGRALDH1A1PTPN5UGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444421-A1 | P-Cadherin antibodies | Pfizer Inc. (US) | 2012-04-25 | — | — | EP | disclosed |