SCHEMBL3445815

SCHEMBL3445815

C=Cc1ccc(OCCCCN(C)C)cc1

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
ALDH1A1 P00352 2/20 0.64
MAOB P27338 2/20 0.58
MAOA P21397 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.56
HRH3 Q9Y5N1 3/20 0.53
CHRNB2 P17787 1/20 0.53
CHRNB4 P30926 1/20 0.53
CHRNA3 P32297 1/20 0.53
CHRNA7 P36544 1/20 0.53
CHRNA4 P43681 1/20 0.53
LSS P48449 1/20 0.51
BCHE P06276 3/20 0.50
ACHE P22303 3/20 0.50
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3444791 0.98 KDM4E (0.62) KDM4EALDH1A1MAOBMAOASMN1; SMN2
SCHEMBL3446469 0.98 KDM4E (0.62) KDM4EALDH1A1MAOBMAOASMN1; SMN2
SCHEMBL98717 0.95 KDM4E (0.62) KDM4EALDH1A1MAOBMAOASMN1; SMN2
SCHEMBL3446237 0.89 HRH3 (0.58) KDM4EALDH1A1SMN1; SMN2HRH3CHRNB2
SCHEMBL1260922 0.85 CHRNA7 (0.61) ALDH1A1SMN1; SMN2CHRNB2CHRNB4CHRNA3
SCHEMBL3444490 0.84 CHRNB2 (0.51) KDM4EALDH1A1MAOBMAOACHRNB2
SCHEMBL3446548 0.83 MAOA (0.60) MAOBMAOACHRNB2CHRNB4CHRNA3
SCHEMBL8754087 0.83 CHRNB2 (0.59) ALDH1A1MAOAHRH3CHRNB2CHRNB4
SCHEMBL1140632 0.83 CHRNB2 (0.59) ALDH1A1MAOAHRH3CHRNB2CHRNB4
SCHEMBL3444158 0.83 CHRNB2 (0.47) KDM4EALDH1A1MAOBMAOACHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
US-7816475-B2 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION (JP) 2010-10-19 US disclosed
EP-1829857-B1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORP (JP) 2009-11-04 EP disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
US-20070213490-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof TOSOH CORPORATION 2007-09-13 US disclosed
EP-1829857-A1 Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof Tosoh Corporation (JP) 2007-09-05 EP disclosed