Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.59 |
| ▸ | LSS | P48449 | 1/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445815 | 0.95 | KDM4E (0.64) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL3444791 | 0.93 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL3446469 | 0.93 | KDM4E (0.62) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL3446237 | 0.91 | HRH3 (0.58) | KDM4EALDH1A1SMN1; SMN2HRH3CHRNB2 | |
| SCHEMBL3446734 | 0.85 | CHRNB2 (0.54) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL9671156 | 0.84 | KDM4E (0.83) | KDM4EALDH1A1SMN1; SMN2HRH3LSS | |
| SCHEMBL3445140 | 0.83 | CHRNB2 (0.55) | KDM4EHRH3CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL1260922 | 0.82 | CHRNA7 (0.61) | ALDH1A1SMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9943360 | 0.82 | CHRNA7 (0.61) | KDM4EALDH1A1SMN1; SMN2CHRNB2CHRNB4 | |
| SCHEMBL3446196 | 0.82 | CHRNB2 (0.48) | KDM4EALDH1A1SMN1; SMN2HRH3LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319394-B2 | Both terminal-modified conjugated diene-based polymer and method for preparing the same | LG CHEM, LTD. | 2022-05-03 | — | — | US | disclosed |
| CN-110475794-B | Conjugated diene polymer modified at both ends and preparation method thereof | 株式会社LG化学 | 2022-03-11 | — | — | CN | disclosed |
| EP-3508509-B1 | BOTH-END-MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PRODUCING SAME | LG CHEMICAL LTD (KR) | 2020-05-13 | — | — | EP | disclosed |
| EP-2569434-B1 | COMPOSITIONS AND METHODS FOR TREATING LEUKEMIA AND RELATED DISORDERS | DANA FARBER CANCER INST INC (US) | 2019-09-04 | — | — | EP | disclosed |
| US-20190263956-A1 | Both Terminal-modified Conjugated Diene-based Polymer And Method For Preparing The Same | LG CHEM, LTD. (KR) | 2019-08-29 | — | — | US | disclosed |
| EP-3508509-A1 | BOTH-END-MODIFIED CONJUGATED DIENE-BASED POLYMER AND METHOD FOR PRODUCING SAME | LG Chem, Ltd. (KR) | 2019-07-10 | — | — | EP | disclosed |
| US-9932309-B2 | 2-oxo-3,4-dihydropyridine-5-carboxylates and their use | UNIVERSITE DE LILLE 2 DROIT ET SANTE (FR) | 2018-04-03 | — | — | US | disclosed |
| US-20170210710-A1 | 2-OXO-3,4-DIHYDROPYRIDINE-5-CARBOXYLATES AND THEIR USE | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2017-07-27 | — | — | US | disclosed |
| US-9260540-B1 | Method of making a functionalized polymer with sulfide linkage | BRIDGESTONE CORPORATION (JP) | 2016-02-16 | — | — | US | disclosed |
| US-9260540-B1 | Method of making a functionalized polymer with sulfide linkage | BRIDGESTONE CORPORATION (JP) | 2016-02-16 | — | — | US | disclosed |
| US-20120059113-A1 | PROCESSING OF RUBBER COMPOSITIONS INCLUDING SILICEOUS FILLERS | BRIDGESTONE CORPORATION (JP) | 2012-03-08 | — | — | US | disclosed |
| US-7816475-B2 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION (JP) | 2010-10-19 | — | — | US | disclosed |
| US-7816475-B2 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION (JP) | 2010-10-19 | — | — | US | disclosed |
| US-7638546-B1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2009-12-29 | — | — | US | disclosed |
| EP-1829857-B1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORP (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-7566734-B2 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, S.A.S. (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20070299073-A1 | Imidazolyl derivatives | IPSEN PHARMA S.A.S. (FR) | 2007-12-27 | — | — | US | disclosed |
| US-20070213490-A1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION | 2007-09-13 | — | — | US | disclosed |
| EP-1829857-A1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | Tosoh Corporation (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-7238695-B2 | Imidazolyl derivatives | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES, SAS (FR) | 2007-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299073-A1 | Imidazolyl derivatives | SSTR5, SSTR3, SSTR2 | KDM4E 3035/4885ALDH1A1 2490/4885SMN1; SMN2 3365/4885 |
| US-20170210710-A1 | 2-OXO-3,4-DIHYDROPYRIDINE-5-CARBOXYLATES AND THEIR USE | CYP3A5, CYP2D6, QDPR | KDM4E 853/4885ALDH1A1 47/4885SMN1; SMN2 1654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.