SCHEMBL3445965

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL475760	0.89	KDM4E (0.56)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL165562	0.83	KDM4E (0.51)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL7868931	0.83	KDM4E (0.51)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL3446204	0.83	CA12 (0.58)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL12180307	0.83	L3MBTL1 (0.51)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL3595760	0.82	L3MBTL1 (0.51)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL17113062	0.82	CA12 (0.46)	KDM4EL3MBTL1ALDH1A1LMNAHSD17B10
	SCHEMBL3446852	0.82	L3MBTL1 (0.50)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL3511987	0.81	LOXL2 (0.49)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA
	SCHEMBL5159229	0.80	KMT2A (0.38)	KDM4EL3MBTL1ALDH1A1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.