Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31649144 | 0.88 | ALDH1A1 (0.41) | KDM4EMAPK1MEN1ALDH1A1HPGD | |
| SCHEMBL31649417 | 0.87 | PTPN11 (0.44) | PTPN11MAPK1MEN1ALDH1A1HPGD | |
| SCHEMBL13107616 | 0.85 | PTPN11 (0.41) | PTPN11KDM4EMAPK1MEN1ALDH1A1 | |
| SCHEMBL31649305 | 0.84 | CYP1A2 (0.40) | MAPK1MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL31737569 | 0.83 | RBP4 (0.34) | KDM4EMAPK1MEN1ALDH1A1HPGD | |
| SCHEMBL31737273 | 0.83 | RBP4 (0.34) | KDM4EMAPK1MEN1ALDH1A1HPGD | |
| SCHEMBL13107734 | 0.83 | ALDH1A1 (0.41) | PTPN11KDM4EMAPK1MEN1ALDH1A1 | |
| SCHEMBL31649023 | 0.81 | KCNH2 (0.38) | PTPN11KDM4EMAPK1MEN1ALDH1A1 | |
| SCHEMBL31649249 | 0.81 | MAPT (0.35) | KDM4EHPGDHSD17B10NPSR1ACHE | |
| SCHEMBL31648858 | 0.81 | PTPN11 (0.35) | PTPN11KDM4EMAPK1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816406-B2 | Quinolone analogs | CYLENE PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20060074089-A1 | Quinolone analogs | SENHWA BIOSCIENCES, INC. (TW) | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074089-A1 | Quinolone analogs | NQO2, BAX, MCL1 | PTPN11 2539/4885KDM4E 1268/4885MAPK1 2899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.