Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 13/20 | 0.46 |
| ▸ | CASP1 | P29466 | 13/20 | 0.46 |
| ▸ | CASP7 | P55210 | 13/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.45 |
| ▸ | USP2 | O75604 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462179 | 0.93 | MERTK (0.43) | CYP1A2ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL34462209 | 0.91 | AXL (0.47) | — | |
| SCHEMBL34462183 | 0.89 | ALDH1A1 (0.51) | CYP1A2ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL34462212 | 0.85 | CDK4 (0.47) | CYP1A2ALDH1A1HSD17B10CASP1CASP7 | |
| SCHEMBL34462226 | 0.83 | SMN1; SMN2 (0.40) | TSHRLMNAPIK3CAPRKDC | |
| SCHEMBL34462340 | 0.83 | AXL (0.47) | — | |
| SCHEMBL34462234 | 0.82 | PRKDC (0.49) | ALDH1A1CASP1CASP7CYP2C9HIF1A | |
| SCHEMBL34462145 | 0.81 | AXL (0.47) | ADORA2AADORA1 | |
| SCHEMBL34462210 | 0.80 | PRKDC (0.49) | ADORA2AADORA1PIK3CAPRKDC | |
| SCHEMBL34462250 | 0.80 | MERTK (0.48) | CYP1A2ALDH1A1HSD17B10CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | claimed |
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |