Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 12/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 11/20 | 0.38 |
| ▸ | FLT3 | P36888 | 9/20 | 0.38 |
| ▸ | GAS6 | Q14393 | 9/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | AXL | P30530 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462314 | 0.95 | MERTK (0.33) | MERTKTYRO3FLT3GAS6TLR7 | |
| SCHEMBL34462303 | 0.92 | ALDH1A1 (0.35) | ADORA3PDE4AADORA2AADORA2BPDE4B | |
| SCHEMBL34462332 | 0.82 | TLR7 (0.36) | TLR7ADORA3PDE4AADORA2AADORA2B | |
| SCHEMBL34462171 | 0.78 | TLR7 (0.37) | MERTKTYRO3FLT3GAS6TLR7 | |
| SCHEMBL34462256 | 0.75 | ADORA2A (0.40) | MERTKTYRO3FLT3GAS6TLR7 | |
| SCHEMBL34462158 | 0.74 | TLR7 (0.36) | MERTKTYRO3FLT3TLR7AXL | |
| SCHEMBL34462349 | 0.72 | MERTK (0.44) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL34462260 | 0.71 | DRD3 (0.37) | MERTKTYRO3FLT3TLR7AXL | |
| SCHEMBL34462167 | 0.71 | ADORA2A (0.39) | MERTKTLR7ADORA2A | |
| SCHEMBL34462336 | 0.65 | ALDH1A1 (0.43) | MERTKADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |