Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462303 | 0.84 | ALDH1A1 (0.35) | PIM1CSNK2A2CSNK2BPIM3PIM2 | |
| SCHEMBL34462314 | 0.83 | MERTK (0.33) | TLR7PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL34462325 | 0.82 | MERTK (0.38) | TLR7ADORA3PDE4AADORA2AADORA2B | |
| SCHEMBL30011988 | 0.77 | ADORA2B (0.45) | GRIN1GRIN2BADORA3PDE4AADORA2A | |
| SCHEMBL34462317 | 0.76 | TLR7 (0.45) | TLR7PIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL34462163 | 0.73 | TLR7 (0.45) | TLR7 | |
| SCHEMBL34462174 | 0.73 | TLR7 (0.45) | TLR7HSD11B1 | |
| SCHEMBL34462275 | 0.72 | TLR7 (0.45) | TLR7 | |
| SCHEMBL34462159 | 0.70 | TLR7 (0.41) | TLR7 | |
| SCHEMBL34462323 | 0.69 | ADORA3 (0.43) | ADORA3ADORA2BMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |