Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 14/20 | 0.44 |
| ▸ | TYRO3 | Q06418 | 12/20 | 0.42 |
| ▸ | FLT3 | P36888 | 10/20 | 0.42 |
| ▸ | GAS6 | Q14393 | 10/20 | 0.42 |
| ▸ | AXL | P30530 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462336 | 0.93 | ALDH1A1 (0.43) | MERTKADORA3ADORA2BCCNE2CCNE1 | |
| SCHEMBL34462276 | 0.88 | ALDH1A1 (0.50) | ADORA3ADORA2BCCNE2CCNE1CDK2 | |
| SCHEMBL34462323 | 0.76 | ADORA3 (0.43) | ADORA3ADORA2BCCNE2CCNE1CDK2 | |
| SCHEMBL34462325 | 0.72 | MERTK (0.38) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL34462340 | 0.71 | AXL (0.47) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL34462209 | 0.71 | AXL (0.47) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL34462145 | 0.71 | AXL (0.47) | MERTKTYRO3FLT3AXL | |
| SCHEMBL34462245 | 0.70 | MERTK (0.43) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL34462186 | 0.70 | MERTK (0.41) | MERTKTYRO3FLT3GAS6AXL | |
| SCHEMBL34462231 | 0.70 | TLR7 (0.54) | MERTKTYRO3FLT3GAS6AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |