Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 8/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 4/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.45 |
| ▸ | MERTK | Q12866 | 4/20 | 0.45 |
| ▸ | GAS6 | Q14393 | 4/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462318 | 0.89 | MERTK (0.47) | FLT3TYRO3MERTKGAS6TLR7 | |
| SCHEMBL34462269 | 0.88 | SIRT5 (0.56) | SIRT5NPSR1RAB9AFLT3TYRO3 | |
| SCHEMBL34462309 | 0.83 | MAPT (0.52) | NPSR1RAB9APDE5AAGTR1AGTR2 | |
| SCHEMBL34462267 | 0.82 | NPSR1 (0.55) | SIRT5NPSR1RAB9AAGTR1AGTR2 | |
| SCHEMBL34462315 | 0.80 | SIRT5 (0.54) | SIRT5NPSR1RAB9AFLT3TYRO3 | |
| SCHEMBL34462331 | 0.78 | NPSR1 (0.57) | SIRT5NPSR1RAB9AAGTR1AGTR2 | |
| SCHEMBL34462293 | 0.77 | TYRO3 (0.53) | FLT3TYRO3MERTKGAS6 | |
| SCHEMBL34462261 | 0.76 | NPSR1 (0.55) | SIRT5NPSR1RAB9AMAPTMEN1 | |
| SCHEMBL30892306 | 0.76 | SIRT5 (0.62) | SIRT5NPSR1RAB9A | |
| SCHEMBL29218450 | 0.76 | SIRT5 (0.62) | SIRT5NPSR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |