Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | JAK3 | P52333 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 2/20 | 0.48 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34462331 | 0.92 | NPSR1 (0.57) | NPSR1RAB9AGAAJAK3MAPT | |
| SCHEMBL34462267 | 0.90 | NPSR1 (0.55) | NPSR1RAB9AGAAJAK3MAPT | |
| SCHEMBL34462269 | 0.88 | SIRT5 (0.56) | NPSR1RAB9AGAAJAK3MAPT | |
| SCHEMBL34462257 | 0.87 | KDM4E (0.53) | GAAJAK3MAPTALDH1A1KDM4E | |
| SCHEMBL18168179 | 0.84 | MAPT (0.56) | NPSR1RAB9AGAAJAK3MAPT | |
| SCHEMBL11084827 | 0.84 | RAB9A (0.61) | NPSR1RAB9AGAAJAK3MAPT | |
| SCHEMBL11159729 | 0.82 | ALDH1A1 (0.66) | NPSR1RAB9AGAAMAPTALDH1A1 | |
| SCHEMBL4712695 | 0.82 | ALDH1A1 (0.65) | NPSR1RAB9AGAAJAK3MAPT | |
| SCHEMBL4847270 | 0.82 | GAA (0.53) | NPSR1RAB9AGAAMAPTPDE4B | |
| SCHEMBL34462295 | 0.81 | SIRT5 (0.50) | NPSR1RAB9AGAAJAK3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724442-A1 | AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF | Council of Scientific and Industrial Research (IN) | 2026-04-15 | — | — | EP | disclosed |