SCHEMBL34463045

SCHEMBL34463045

COc1c(F)ccc(F)c1CCN

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 11/20 0.52
HTR2A P28223 2/20 0.42
HTR2C P28335 2/20 0.42
HTR2B P41595 2/20 0.42
CYP1A2 P05177 1/20 0.38
MAOB P27338 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ATM Q13315 1/20 0.37
HTR1D P28221 1/20 0.36
HTR6 P50406 1/20 0.36
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34462981 0.86 TAAR1 (0.47) TAAR1HTR2AHTR2CHTR2BCYP1A2
SCHEMBL19743855 0.85 TAAR1 (0.39) TAAR1HTR2AHTR2CHTR2BCYP1A2
SCHEMBL24180080 0.83 HMGCR (0.37) TAAR1HTR2AHTR2CHTR2BKDM4E
SCHEMBL17119684 0.77 MEP1B (0.36) TAAR1HTR2AHTR2CHTR2BKDM4E
SCHEMBL17119690 0.77 CA2 (0.42) TAAR1KDM4EMAPK1
SCHEMBL6953459 0.76 TAAR1 (0.48) TAAR1HTR2AHTR2CHTR2BCYP1A2
SCHEMBL27668305 0.76 MEP1B (0.47) TAAR1HTR2AHTR2CHTR2BCYP1A2
Hydrochloric Acid SCHEMBL27730362 0.75 MEP1B (0.46) TAAR1HTR2AHTR2CHTR2BCYP1A2
SCHEMBL9873091 0.74 KDM4E (0.43) KDM4EMAPK1
SCHEMBL22391550 0.73 MEP1B (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 EP disclosed