Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437058 | 0.87 | TUBB1 (0.36) | KDM4EALDH1A1MAPK1SMN1; SMN2MEP1B | |
| SCHEMBL1994314 | 0.85 | MEP1B (0.41) | KDM4EALDH1A1MAPK1SMN1; SMN2CA12 | |
| SCHEMBL23829848 | 0.84 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPK1SMN1; SMN2MEP1B | |
| SCHEMBL10209739 | 0.84 | CA2 (0.43) | KDM4EALDH1A1MAPK1SMN1; SMN2CA1 | |
| SCHEMBL14037359 | 0.83 | KDM4E (0.36) | KDM4EALDH1A1MAPK1SMN1; SMN2CA12 | |
| SCHEMBL475141 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPK1SMN1; SMN2CA12 | |
| SCHEMBL7962496 | 0.81 | PDE4A (0.39) | KDM4EALDH1A1MAPK1SMN1; SMN2MEP1B | |
| SCHEMBL23324806 | 0.81 | KDM4E (0.35) | KDM4EALDH1A1MAPK1SMN1; SMN2MEP1B | |
| SCHEMBL23894376 | 0.81 | HTR2A (0.38) | KDM4EALDH1A1MAPK1SMN1; SMN2MEP1B | |
| SCHEMBL746439 | 0.81 | CA4 (0.39) | KDM4EALDH1A1MAPK1SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037983-A | 6,7-dihydroxyquinoxalines as intermediates to beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4904775-A | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics | E. R. SQUIBB & SONS, INC. (US) | 1990-02-27 | — | — | US | disclosed |
| EP-0342423-A2 | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics | E.R. SQUIBB & SONS, INC. (US) | 1989-11-23 | — | — | EP | disclosed |