SCHEMBL29408579

SCHEMBL29408579

Cc1cn([C@H]2C[C@H](OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3OP(=O)(O)OC[C@H]3O[C@@H](n4cnc5c(=O)[nH]c(N)nc54)C[C@@H]3OP(=O)(O)O)[C@@H](COP(=O)(O)O[C@H]3C[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3COP(=O)(O)O[C@H]3C[C@H](n4cnc5c(=O)[nH]c(N)nc54)O[C@@H]3CO)O2)c(=O)[nH]c1=O

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.62
▸ TERT O14746 2/20 0.54
▸ POLB P06746 2/20 0.53
▸ P2RY2 P41231 1/20 0.52
▸ P2RY4 P51582 1/20 0.52
▸ P2RY6 Q15077 1/20 0.52
▸ DTYMK P23919 4/20 0.52
▸ TK1 P04183 2/20 0.51
▸ FUT5 Q11128 1/20 0.51
▸ P2RY1 P47900 1/20 0.50
▸ POLA1 P09884 1/20 0.47
▸ POLD1 P28340 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29671382 0.95 F2 (0.68) F2TERTPOLBP2RY2P2RY4
SCHEMBL29775052 0.95 F2 (0.68) F2TERTPOLBP2RY2P2RY4
SCHEMBL29350192 0.95 F2 (0.68) F2TERTPOLBP2RY2P2RY4
SCHEMBL29415903 0.95 F2 (0.68) F2TERTPOLBP2RY2P2RY4
SCHEMBL34463741 0.95 F2 (0.68) F2TERTPOLBP2RY2P2RY4
SCHEMBL17742358 0.92 F2 (0.57) F2TERTPOLBP2RY2P2RY4
SCHEMBL15672415 0.92 F2 (0.65) F2TERTPOLBP2RY2P2RY4
SCHEMBL18362678 0.92 F2 (0.59) F2TERTPOLBP2RY2P2RY4
SCHEMBL18760797 0.92 F2 (0.59) F2TERTPOLBP2RY2P2RY4
SCHEMBL18760794 0.92 F2 (0.59) F2TERTPOLBP2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207409-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES CIVI BIOPHARMA INC (US) 2024-06-27 — — US claimed
EP-4326329-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES Civi Biopharma, Inc. (US) 2024-02-28 — — EP claimed
CN-117545509-A Oral delivery of oligonucleotides 四纬生物制药股份有限公司 2024-02-09 — — CN claimed
WO-2024030909-A1 BIOMARKERS OF AMINO ACID COMPOSITION TREATMENT RESPONSE IN LONG COVID AXCELLA HEALTH INC. (US) 2024-02-08 — — WO claimed
WO-2024026307-A1 BIOMARKER FOR LONG COVID AND FATIGUE AXCELLA HEALTH INC. (US) 2024-02-01 — — WO claimed
US-20230218596-A1 METHODS INVOLVING NEUTROPHIL ELASTASE INHIBITOR ALVELESTAT FOR TREATING CORONAVIRUS INFECTION MEREO BIOPHARMA 4 LIMITED (GB) 2023-07-13 — — US claimed
US-20220380761-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES CIVI BIOPHARMA, INC. (US) 2022-12-01 — — US claimed
WO-2022226217-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES CIVI BIOPHARMA, INC. (US) 2022-10-27 — — WO claimed
US-20260131007-A1 Mannose 6-Phosphate Receptor Binding Compounds for the Degradation of Extracellular Proteins AVILAR THERAPEUTICS, INC. (US) 2026-05-14 — — US disclosed
US-12606828-B2 Aptamers for use in the treatment of Coronaviridae infections APTA Therapeutics GmbH (DE) 2026-04-21 — — US disclosed
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2026-03-26 — — US disclosed
US-12553054-B2 Compositions and methods related to nucleic acid anticoagulants NORTH CAROLINA STATE UNIVERSITY (US) 2026-02-17 — — US disclosed
EP-4678749-A1 NEUTRALIZABLE BLOOD COAGULATION INHIBITOR The University of Tokyo (JP) 2026-01-14 — — EP disclosed
WO-2025235814-A1 POTENT ASGPR-BINDING HETEROBIFUCTIONAL COMPOUNDS FOR THE DEGRADATION OF TARGETED EXTRACELLULAR PROTEINS AVILAR THERAPEUTICS, INC. (US) 2025-11-13 — — WO disclosed
US-20220380761-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES CIVI BIOPHARMA, INC. (US) 2022-12-01 — — US disclosed
WO-2022226217-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES CIVI BIOPHARMA, INC. (US) 2022-10-27 — — WO disclosed
WO-2022214670-A1 APTAMERS FOR USE IN THE TREATMENT OF CORONAVIRIDAE INFECTIONS Berlin Cures GmbH (DE) 2022-10-13 — — WO disclosed
WO-2022058755-A1 SELF-TARGETING EXPRESSION VECTOR Lightbio Limited (GB) 2022-03-24 — — WO disclosed
US-11282276-B2 Collaborative light show authoring for tessellated geometries CONTRAVENTUM, LLC (US) 2022-03-22 — — US disclosed
US-20220056068-A1 LIGAND DETECTION BY APTAMERS WITH A BUILT-IN REPORTER KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2022-02-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12553054-B2 Compositions and methods related to nucleic acid anticoagulants NSUN2, NSUN3, ADAR F2 16/4885TERT 340/4885POLB 635/4885
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS ASGR1, FCGR2A, FCGR3B F2 2402/4885TERT 4863/4885POLB 4359/4885
US-12606828-B2 Aptamers for use in the treatment of Coronaviridae infections DNTT, TPT1, TEKT1 F2 20/4885TERT 17/4885POLB 258/4885
US-20240207409-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES RNGTT, RNMT, SRRT F2 4885/4885TERT 3199/4885POLB 1103/4885
US-20220056068-A1 LIGAND DETECTION BY APTAMERS WITH A BUILT-IN REPORTER IGF2R, NCS1, KCNJ6 F2 4578/4885TERT 2383/4885POLB 3537/4885
US-20260131007-A1 Mannose 6-Phosphate Receptor Binding Compounds for the Degradation of Extracellular Proteins IGF2R, M6PR, MSR1 F2 4029/4885TERT 4830/4885POLB 4477/4885
US-20230218596-A1 METHODS INVOLVING NEUTROPHIL ELASTASE INHIBITOR ALVELESTAT FOR TREATING CORONAVIRUS INFECTION SERPINB1, ELANE, MPO F2 794/4885TERT 429/4885POLB 628/4885
US-20220380761-A1 ORAL DELIVERY OF OLIGONUCLEOTIDES RNGTT, RNMT, SRRT F2 4885/4885TERT 3199/4885POLB 1103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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