SCHEMBL34465992

SCHEMBL34465992

COCC(=O)N1C[C@H](C)n2nc3c(F)c(Cl)c(Br)cc3c2[C@@H]1C

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35212007 0.90 MEN1 (0.32) —
SCHEMBL34466692 0.89 — —
SCHEMBL34466694 0.89 — —
SCHEMBL34467127 0.89 — —
SCHEMBL35212284 0.89 SUV39H2 (0.34) CCR1
SCHEMBL35211741 0.89 SUV39H2 (0.34) CCR1
SCHEMBL34466554 0.89 CFD (0.30) —
Hydrochloric Acid SCHEMBL34466899 0.88 CFD (0.30) —
SCHEMBL34466256 0.85 CCR1 (0.32) CCR1
SCHEMBL35212023 0.85 CFD (0.33) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109704-A1 5-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-04-23 — — US disclosed
US-20260108509-A1 6-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109704-A1 5-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF CGAS, GBA3, CYP11B2 CCR1 1423/4885
US-20260108509-A1 6-MEMBERED HETEROARYL INDAZOLE CGAS INHIBITORS AND USES THEREOF CGAS, GBA3, GBA1 CCR1 699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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