SCHEMBL35211741

SCHEMBL35211741

COCC(=O)N1C[C@H](C)n2nc3c(F)c(Cl)c(OC)cc3c2[C@H]1C

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SUV39H2 Q9H5I1 2/20 0.34
▸ CFD P00746 5/20 0.33
▸ CCR1 P32246 6/20 0.32
▸ ADAMTS5 Q9UNA0 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35212284 1.00 SUV39H2 (0.34) SUV39H2CFDCCR1ADAMTS5
SCHEMBL35212289 0.92 CFD (0.32) CFDCCR1
SCHEMBL35211723 0.92 CFD (0.32) CFDCCR1
SCHEMBL35212411 0.91 CFD (0.34) CFDCCR1ADAMTS5
SCHEMBL35212616 0.91 CFD (0.34) CFDCCR1ADAMTS5
SCHEMBL35212352 0.90 SUV39H2 (0.32) SUV39H2CFD
SCHEMBL35212318 0.90 SUV39H2 (0.32) SUV39H2CFD
SCHEMBL35212023 0.89 CFD (0.33) SUV39H2CFD
SCHEMBL34465992 0.89 CCR1 (0.31) CCR1
SCHEMBL34466554 0.89 CFD (0.30) CFD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125383-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF VENTUS THERAPEUTICS U.S., INC. (US) 2026-05-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125383-A1 INDAZOLE INHIBITORS OF CYCLIC GMP-AMP SYNTHASE AND USES THEREOF CGAS, PRKG1, GMPS SUV39H2 4809/4885CFD 4697/4885CCR1 930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback