Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25681517 | 1.00 | ALOX5AP (0.52) | ALOX5APPIK3CDPIP5K1CPIK3CAPI4KA | |
| SCHEMBL25681516 | 0.84 | NTRK1 (0.45) | ALOX5APPIK3CDPIP5K1CPIK3CAPI4KA | |
| SCHEMBL25681519 | 0.82 | ALOX5AP (0.47) | ALOX5APPIK3CDPIP5K1CPIK3CAPI4KA | |
| SCHEMBL25682150 | 0.81 | ALOX5AP (0.39) | ALOX5APBACE1CYP11B2ALDH1A1 | |
| SCHEMBL14097461 | 0.80 | HTR1D (0.57) | ALOX5APPIK3CDPIP5K1CPIK3CAPI4KA | |
| SCHEMBL12051553 | 0.80 | ALOX5AP (0.49) | ALOX5APPIK3CDPIP5K1CPIK3CAPI4KA | |
| SCHEMBL25168404 | 0.78 | ABL1 (0.51) | ALOX5APCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL31258632 | 0.78 | ABL1 (0.51) | ALOX5APCYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL12051554 | 0.77 | ALOX5AP (0.47) | ALOX5APPIK3CDPIP5K1CPIK3CAPI4KA | |
| SCHEMBL10176218 | 0.76 | CYP11B2 (0.60) | ALOX5APMKNK1MKNK2MEN1PSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260109709-A1 | 2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS | MIRATI THERAPEUTICS INC (US) | 2026-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260109709-A1 | 2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS | PRMT5, PRMT1, PRMT3 | ALOX5AP 4763/4885PIK3CD 2161/4885PIP5K1C 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.