Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34467680 | 0.83 | CTSK (0.45) | CTSKCTSLCTSSTDP1ATM | |
| SCHEMBL34467659 | 0.83 | TDP1 (0.48) | TDP1ATMMAPTNPSR1MEN1 | |
| SCHEMBL34467675 | 0.83 | TDP1 (0.43) | TDP1ATMMAPTNPSR1MEN1 | |
| SCHEMBL34467668 | 0.81 | TDP1 (0.42) | TDP1ATMMAPTNPSR1MEN1 | |
| SCHEMBL31300274 | 0.80 | HDAC3 (0.39) | CTSKCTSLCTSSKMT2AALDH1A1 | |
| SCHEMBL31300279 | 0.80 | HDAC3 (0.39) | CTSKCTSLCTSSKMT2AALDH1A1 | |
| SCHEMBL34467669 | 0.76 | HDAC3 (0.41) | TDP1ATMMAPTMEN1KMT2A | |
| SCHEMBL34467674 | 0.71 | NPSR1 (0.47) | CTSKTDP1ATMMAPTNPSR1 | |
| SCHEMBL31758256 | 0.70 | TDP1 (0.61) | CTSKCTSSTDP1ATMMAPT | |
| SCHEMBL17309872 | 0.68 | MAPT (0.68) | TDP1MAPTNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260117274-A1 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | UNIV NEW YORK STATE RES FOUND (US) | 2026-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260117274-A1 | ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF | PTMS, PSMG3, PSMB3 | CTSK 3616/4885CTSL 2443/4885CTSS 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.