SCHEMBL34467680

SCHEMBL34467680

CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)n1ncc(-c2cccs2)n1)C(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 3/20 0.45
▸ CTSS P25774 2/20 0.45
▸ CTSL P07711 1/20 0.45
▸ TDP1 Q9NUW8 8/20 0.42
▸ ATM Q13315 2/20 0.42
▸ NPSR1 Q6W5P4 8/20 0.41
▸ MEN1 O00255 5/20 0.41
▸ KMT2A Q03164 5/20 0.41
▸ MAPT P10636 5/20 0.41
▸ POLB P06746 4/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ PAX8 Q06710 1/20 0.41
▸ P2RY2 P41231 1/20 0.40
▸ KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34467674 0.87 NPSR1 (0.47) CTSKTDP1ATMNPSR1MEN1
SCHEMBL34467667 0.83 TDP1 (0.42) TDP1ATMNPSR1MEN1KMT2A
SCHEMBL34467657 0.83 CTSK (0.47) CTSKCTSSCTSLTDP1ATM
SCHEMBL34467682 0.83 P2RY2 (0.49) TDP1ATMNPSR1MEN1KMT2A
SCHEMBL34467686 0.83 TDP1 (0.43) TDP1ATMNPSR1MEN1KMT2A
SCHEMBL34467670 0.81 TDP1 (0.42) TDP1ATMNPSR1MEN1KMT2A
SCHEMBL34467681 0.81 TDP1 (0.48) TDP1ATMNPSR1MEN1KMT2A
SCHEMBL31300259 0.80 CAMK2D (0.35) CTSKCTSSCTSLMEN1KMT2A
SCHEMBL34467678 0.76 CAMK2D (0.37) TDP1ATMMEN1KMT2AMAPT
SCHEMBL31758256 0.70 TDP1 (0.61) CTSKCTSSTDP1ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117274-A1 ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF UNIV NEW YORK STATE RES FOUND (US) 2026-04-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117274-A1 ORTHOGONALLY CROSSLINKED PROTEINS, METHODS OF MAKING, AND USES THEREOF PTMS, PSMG3, PSMB3 CTSK 3616/4885CTSS 3065/4885CTSL 2443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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