Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.77 |
| ▸ | TP53 | P04637 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.70 |
| ▸ | CNR2 | P34972 | 2/20 | 0.67 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TLR2 | O60603 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13561104 | 0.87 | MAPT (1.00) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL34468494 | 0.86 | MAPT (0.70) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL34468641 | 0.86 | MAPT (0.84) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL15347034 | 0.84 | POLB (0.81) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL34468564 | 0.84 | ALDH1A1 (0.96) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL34468508 | 0.83 | ALDH1A1 (0.79) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL34468615 | 0.83 | ALDH1A1 (0.69) | MAPTALDH1A1KDM4EHPGDTHRB | |
| SCHEMBL1038897 | 0.82 | PDE4D (1.00) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL34468567 | 0.81 | ALDH1A1 (0.75) | MAPTTP53ALDH1A1KDM4EHPGD | |
| SCHEMBL34468525 | 0.81 | MAPT (0.76) | MAPTTP53ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | claimed |
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | SRR, APEH, OSR1 | MAPT 4472/4885TP53 3356/4885ALDH1A1 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.