Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.96 |
| ▸ | POLB | P06746 | 2/20 | 0.96 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | CNR2 | P34972 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TLR2 | O60603 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34468567 | 0.88 | ALDH1A1 (0.75) | ALDH1A1POLBPDE4DMAPTHSD17B10 | |
| SCHEMBL34468601 | 0.85 | MAPT (0.71) | ALDH1A1POLBPDE4DMAPTHSD17B10 | |
| SCHEMBL34468548 | 0.84 | MAPT (0.77) | ALDH1A1POLBPDE4DMAPTHSD17B10 | |
| SCHEMBL15347034 | 0.83 | POLB (0.81) | ALDH1A1POLBPDE4DMAPTHSD17B10 | |
| SCHEMBL34468494 | 0.82 | MAPT (0.70) | ALDH1A1POLBPDE4DMAPTHSD17B10 | |
| SCHEMBL34468641 | 0.82 | MAPT (0.84) | ALDH1A1POLBPDE4DMAPTHSD17B10 | |
| SCHEMBL34468566 | 0.82 | ALDH1A1 (0.69) | ALDH1A1POLBMAPTHSD17B10TSHR | |
| SCHEMBL34468608 | 0.82 | POLB (0.79) | ALDH1A1POLBPDE4DMAPTHSD17B10 | |
| SCHEMBL34468508 | 0.80 | ALDH1A1 (0.79) | ALDH1A1POLBPDE4DMAPTHSD17B10 | |
| SCHEMBL34468525 | 0.80 | MAPT (0.76) | ALDH1A1POLBPDE4DMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | claimed |
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | TEXAS CROP SCIENCE INC (US) | 2026-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260116872-A1 | THIOPHENE BASED APYRASE INHIBITORS | SRR, APEH, OSR1 | ALDH1A1 2701/4885POLB 4075/4885PDE4D 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.