SCHEMBL34470

SCHEMBL34470

Oc1ncnc2c1ncn2[C@@H]1O[C@H](CS)[C@@H](O)[C@H]1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.62
DOT1L Q8TEK3 2/20 0.62
DPP4 P27487 1/20 0.62
MEN1 O00255 1/20 0.62
SLC28A1 O00337 1/20 0.62
MAP3K7 O43318 1/20 0.62
SLC28A2 O43868 1/20 0.62
GAPDH P04406 1/20 0.62
ADORA3 P0DMS8 1/20 0.62
MAPK1 P28482 1/20 0.62
ADORA2A P29274 1/20 0.62
ADORA2B P29275 1/20 0.62
STAT6 P42226 1/20 0.62
PI4KA P42356 1/20 0.62
KMT2A Q03164 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
PI4K2B Q8TCG2 1/20 0.62
SLC29A1 Q99808 1/20 0.62
PI4K2A Q9BTU6 1/20 0.62
SLC28A3 Q9HAS3 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Inosine SCHEMBL15804 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL18653532 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL20138477 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL298755 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL4110068 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL2046912 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL6748954 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL12763613 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL330178 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1
Inosine SCHEMBL2229394 0.88 SLC29A1 (0.75) ADORA1DOT1LDPP4MEN1SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1723 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022144780-A1 SULFONAMIDE DERIVATIVES, COMPOSITIONS COMPRISING SAME AND USES THEREOF IN THE TREATMENT OF CANCERS NATIONAL CANCER CENTER (JP) 2022-07-07 WO claimed
EP-3463384-A1 CANCER TREATMENTS NuCana plc (GB) 2019-04-10 EP claimed
WO-2017207993-A1 CANCER TREATMENTS NUCANA BIOMED LIMITED (GB) 2017-12-07 WO claimed
US-9179994-B2 Implantable film/mesh composite COVIDIEN LP (US) 2015-11-10 US claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-9005308-B2 Implantable film/mesh composite for passage of tissue therebetween COVIDIEN LP (US) 2015-04-14 US claimed
US-8932621-B2 Implantable film/mesh composite COVIDIEN LP (US) 2015-01-13 US claimed
US-20140142520-A1 IMPLANTABLE DEVICES INCLUDING A MESH AND A PIVOTABLE FILM COVIDIEN LP (US) 2014-05-22 US claimed
EP-2586400-B1 Implantable film/Mesh composite COVIDIEN LP (US) 2014-03-19 EP claimed
EP-2586401-B1 Implantable film/mesh composite COVIDIEN LP (US) 2014-03-19 EP claimed
US-20020010210-A1 PHARMACEUTICAL PREPARATION AND METHOD FOR TREATING CANCER SHOWA DENKO KABUSHIKI KAISHA (JP) 2002-01-24 US claimed
US-20010049349-A1 Antioxidant enhancement of therapy for hyperproliferative conditions CRABTREE ACQUISITION CO, LLC 2001-12-06 US claimed
EP-1019034-A2 ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS Atherogenics, Inc. (US) 2000-07-19 EP claimed
WO-1999001118-A9 ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS ATHEROGENICS INC (US) 1999-05-20 WO claimed
WO-1999001118-A2 ANTIOXIDANT ENHANCEMENT OF THERAPY FOR HYPERPROLIFERATIVE CONDITIONS ATHEROGENICS, INC. (US) 1999-01-14 WO claimed
EP-0875246-A1 Pharmaceutical preparation of ascorbic acid derivatives for medical treatment of cancer SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-11-04 EP claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
EP-0608546-A2 Glia activating factor (GAF), antibodies against it and their uses TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-08-03 EP claimed
EP-0476711-A2 Use of 5-fluorouracil for the treatment of AIDS Nakai, Masuyo (JP) 1992-03-25 EP claimed
EP-0302263-A2 Therapeutic composition for combatting AIDS Nakai, Masuyo (JP) 1989-02-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010210-A1 PHARMACEUTICAL PREPARATION AND METHOD FOR TREATING CANCER PROC, CYP27B1, SLC46A1 ADORA1 1065/4885DOT1L 4679/4885DPP4 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.