SCHEMBL3447141

SCHEMBL3447141

COOC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA1 P30542 5/20 0.71
▸ SMN1; SMN2 Q16637 3/20 0.71
▸ ADORA3 P0DMS8 2/20 0.71
▸ ADORA2A P29274 2/20 0.71
▸ ADORA2B P29275 2/20 0.71
▸ DPP4 P27487 1/20 0.71
▸ MEN1 O00255 1/20 0.71
▸ SLC28A1 O00337 1/20 0.71
▸ MAP3K7 O43318 1/20 0.71
▸ SLC28A2 O43868 1/20 0.71
▸ GAPDH P04406 1/20 0.71
▸ MAPK1 P28482 1/20 0.71
▸ STAT6 P42226 1/20 0.71
▸ PI4KA P42356 1/20 0.71
▸ KMT2A Q03164 1/20 0.71
▸ PI4K2B Q8TCG2 1/20 0.71
▸ DOT1L Q8TEK3 1/20 0.71
▸ SLC29A1 Q99808 1/20 0.71
▸ PI4K2A Q9BTU6 1/20 0.71
▸ SLC28A3 Q9HAS3 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15788449 0.91 ADORA1 (0.74) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
SCHEMBL15926827 0.91 ADORA1 (0.74) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
SCHEMBL384075 0.91 ADORA1 (0.74) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
SCHEMBL29936504 0.91 ADORA1 (0.74) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
SCHEMBL15338502 0.91 ADORA1 (0.74) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
SCHEMBL15338536 0.91 ADORA1 (0.74) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
SCHEMBL41361 0.91 ADORA1 (0.74) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
SCHEMBL3446755 0.90 ADORA1 (0.71) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
SCHEMBL8164443 0.89 P2RY1 (0.68) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B
Water SCHEMBL4262656 0.89 ADORA1 (0.71) ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103319555-A Preparation method of 2'-methoxy adenosine HUAIHAI INST TECHNOLOGY 2013-09-25 — — CN claimed
CN-102058614-A Use of adenosine receptor agonists in therapy CAMBRIDGE BIOTECHNOLOGY LTD 2011-05-18 — — CN claimed
CN-100355769-C 2'-methoxy adenosine preparation method UNIV EAST CHINA NORMAL (CN) 2007-12-19 — — CN claimed
CN-1886414-A Improved synthesis of 2-substituted adenosines BIOVITRUM AB (SE) 2006-12-27 — — CN claimed
CN-1765913-A 2'-methoxy adenosine preparation method UNIV EAST CHINA NORMAL (CN) 2006-05-03 — — CN claimed
WO-1999051761-A1 IMPROVEMENTS IN OR RELATING TO NUCLEIC ACID SYNTHESIS AND SELECTION MEDICAL RESEARCH COUNCIL (GB) 1999-10-14 — — WO claimed
WO-2025125630-A1 METHOD FOR BIOPROTAC DESIGN MEDIMMUNE LIMITED (GB) 2025-06-19 — — WO disclosed
CN-120157727-A Chemically modified adenine nucleoside triphosphate and preparation method and application thereof 中国科学院深圳先进技术研究院 2025-06-17 — — CN disclosed
CN-120118909-A SiRNA duplex for targeted regulation of LPA gene expression and application thereof in preventing and treating cardiovascular and cerebrovascular related diseases 北京悦康科创医药科技股份有限公司 2025-06-10 — — CN disclosed
CN-119799706-A SiRNA for targeted regulation of HBV gene expression and application thereof 杭州天龙药业有限公司 2025-04-11 — — CN disclosed
CN-119799705-A SiRNA for targeted regulation of HBV gene expression and application thereof 杭州天龙药业有限公司 2025-04-11 — — CN disclosed
CN-119752912-A SiRNA for targeted regulation of HBV gene expression and application thereof 杭州天龙药业有限公司 2025-04-04 — — CN disclosed
CN-119219711-B Preparation method of 2' -modified basic nucleoside 上海科泽永欣生物科技有限公司 2025-03-14 — — CN disclosed
US-20050043268-A1 Inhibition of viruses MEDICAL RESEARCH COUNCIL (GB) 2005-02-24 — — US disclosed
WO-2004078183-A1 COMPOUNDS FOR THE TREATMENT OF PAIN CAMBRIDGE BIOTECHNOLOGY LTD (GB) 2004-09-16 — — WO disclosed
WO-1999051761-A1 IMPROVEMENTS IN OR RELATING TO NUCLEIC ACID SYNTHESIS AND SELECTION MEDICAL RESEARCH COUNCIL (GB) 1999-10-14 — — WO disclosed
WO-1998001459-A1 NOVEL N-ALKOXYADENINE DERIVATIVES ACTING AS CYTOKINE INHIBITORS NOVO NORDISK A/S (DK) 1998-01-15 — — WO disclosed
WO-1997033591-A1 A METHOD OF TREATING DISORDERS RELATED TO CYTOKINES IN MAMMALS NOVO NORDISK A/S (DK) 1997-09-18 — — WO disclosed
EP-0719275-A1 CHEMICAL COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1996-07-03 — — EP disclosed
WO-1995007921-A1 CHEMICAL COMPOUNDS, THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1995-03-23 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043268-A1 Inhibition of viruses RNASE1, HNRNPA1, RNASEH1 ADORA1 237/4885SMN1; SMN2 421/4885ADORA3 399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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