Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 2/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 2/20 | 0.48 |
| ▸ | KLK1 | P06870 | 2/20 | 0.48 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7420599 | 0.98 | CYP17A1 (0.58) | CYP17A1AURKARPS6KB1DRD2PTGDR2 | |
| SCHEMBL5106837 | 0.87 | CYP17A1 (0.57) | CYP17A1AURKARPS6KB1DRD2PTGDR2 | |
| SCHEMBL132701 | 0.86 | CYP17A1 (0.76) | CYP17A1DRD2PTGDR2MAPK14NAMPT | |
| SCHEMBL13055402 | 0.86 | CYP17A1 (0.59) | CYP17A1DRD2PTGDR2MAPK14NAMPT | |
| SCHEMBL2243542 | 0.85 | CYP17A1 (0.46) | CYP17A1AURKARPS6KB1DRD2PTGDR2 | |
| SCHEMBL14547187 | 0.85 | CYP17A1 (0.46) | CYP17A1AURKARPS6KB1DRD2PTGDR2 | |
| SCHEMBL10361607 | 0.85 | CYP17A1 (0.61) | CYP17A1DRD2PTGDR2MAPK14NAMPT | |
| SCHEMBL245094 | 0.85 | CYP17A1 (0.61) | CYP17A1AURKARPS6KB1DRD2PTGDR2 | |
| SCHEMBL6195004 | 0.85 | CYP17A1 (0.61) | CYP17A1AURKARPS6KB1DRD2PTGDR2 | |
| SCHEMBL29969056 | 0.84 | AURKA (0.52) | CYP17A1AURKARPS6KB1LOXL2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898193-B | Indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2022-08-05 | — | — | CN | claimed |
| CN-112898193-A | Indole aryl sulfone derivative and preparation method and application thereof | 山东大学 | 2021-06-04 | — | — | CN | claimed |
| US-20260125376-A1 | IRREVERSIBLE INACTIVATORS TARGETING ARAF/MEK COMPLEXES | GERO THOMAS (US) | 2026-05-07 | — | — | US | disclosed |
| EP-4073062-B1 | FUNCTIONALIZED HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | RYVU THERAPEUTICS S A (PL) | 2026-04-29 | — | — | EP | disclosed |
| CN-121574171-A | Difunctional protein degradation agent of direct targeting proteasome, preparation method and application thereof | 浙大城市学院 | 2026-02-27 | — | — | CN | disclosed |
| EP-4598521-A2 | IRREVERSIBLE INACTIVATORS TARGETING ARAF/MEK COMPLEXES | Dana-Farber Cancer Institute, Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| US-20250230124-A1 | SMALL MOLECULE INHIBITORS OF ID PROTEINS | MEMORIAL SLOAN KETTERING CANCER CENTER (US) | 2025-07-17 | — | — | US | disclosed |
| EP-3493851-B1 | NOVEL SCAFFOLDS FOR INTRACELLULAR COMPOUND DELIVERY FOR THE DETECTION OF CANCER CELLS | ISI LIFE SCIENCES INC (US) | 2025-06-25 | — | — | EP | disclosed |
| US-20250170104-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-05-29 | — | — | US | disclosed |
| CN-119855612-A | Radionuclide coupling medicine, pharmaceutical composition and application thereof | 同宜医药（苏州）有限公司 | 2025-04-18 | — | — | CN | disclosed |
| WO-2025049326-A1 | TRICYCLIC HETEROAROMATIC INHIBITORS OF KLK5 | BIOCRYST PHARMACEUTICALS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| EP-0854867-B1 | TETRAHYDROQUINOLINES AS NMDA ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 2002-07-31 | — | — | EP | disclosed |
| EP-1115731-A2 | NOVEL PYRANOSES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2001-07-18 | — | — | EP | disclosed |
| US-6211228-B1 | COMPOUNDS WITH AMINO, GUANIDINO AND AMIDINO HETEROCYCLIC COMPOUNDS | AXYS PHARMACEUTICALS, INC | 2001-04-03 | — | — | US | disclosed |
| WO-2000014097-A2 | NOVEL PYRANOSES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-03-16 | — | — | WO | disclosed |
| US-6022969-A | Compositions and methods for treating mast-cell mediated conditions | AXYS PHARMACEUTICALS, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5977136-A | Tetrahydroquinolines as NMDA antagonists | GLAXO WELLCOME SPA (IT) | 1999-11-02 | — | — | US | disclosed |
| CN-1160398-A | Compositions and methods for treating mast-cell inflammatory condition | ARRIS PHARM CORP (US) | 1997-09-24 | — | — | CN | disclosed |
| EP-0782571-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1997-07-09 | — | — | EP | disclosed |
| WO-1996009297-A1 | COMPOSITIONS AND METHODS FOR TREATING MAST-CELL INFLAMMATORY CONDITION | ARRIS PHARMACEUTICAL CORPORATION (US) | 1996-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125376-A1 | IRREVERSIBLE INACTIVATORS TARGETING ARAF/MEK COMPLEXES | ARAF, BRAF, RAF1 | CYP17A1 4431/4885AURKA 477/4885RPS6KB1 220/4885 |
| US-20250230124-A1 | SMALL MOLECULE INHIBITORS OF ID PROTEINS | ING2, EDF1, DAB2IP | CYP17A1 4647/4885AURKA 2612/4885RPS6KB1 1743/4885 |
| US-20250170104-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | LTA, SERPINB1, LAS1L | CYP17A1 3451/4885AURKA 4335/4885RPS6KB1 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.