SCHEMBL3448180

SCHEMBL3448180

CC(C)(O)C#Cc1ccc(N)cc1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.54
MAPT P10636 4/20 0.46
ASIC3 Q9UHC3 1/20 0.44
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
HAO1 Q9UJM8 1/20 0.39
HTT P42858 1/20 0.39
PIKFYVE Q9Y2I7 3/20 0.39
PAK4 O96013 3/20 0.39
TTBK1 Q5TCY1 3/20 0.39
PTGES2 Q9H7Z7 2/20 0.39
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
PAK1 Q13153 1/20 0.38
PKN1 Q16512 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12391039 0.89 ASIC3 (0.50) MAPTASIC3LMNAL3MBTL1HAO1
SCHEMBL20717544 0.82 APP (0.59) APPMAPTHAO1PTGES2
SCHEMBL12711667 0.80 APP (0.47) APPMAPTASIC3LMNAL3MBTL1
SCHEMBL14268091 0.80 ASIC3 (0.49) MAPTASIC3LMNAL3MBTL1HAO1
SCHEMBL18561130 0.78 MAPT (0.53) APPMAPTASIC3LMNAL3MBTL1
SCHEMBL700507 0.78 HTT (0.46) APPMAPTASIC3LMNAL3MBTL1
SCHEMBL6865029 0.78 KIF11 (0.45) MAPTASIC3LMNAL3MBTL1HAO1
SCHEMBL1571249 0.78 ASIC3 (0.44) APPMAPTASIC3LMNAL3MBTL1
SCHEMBL13692776 0.78 ASIC3 (0.44) MAPTASIC3LMNAL3MBTL1HAO1
SCHEMBL8620900 0.78 ASIC3 (0.44) MAPTASIC3LMNAL3MBTL1HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119330839-A Method for preparing p-aminophenylacetylene 金泰旭化学技术(无锡)有限公司 2025-01-21 CN claimed
WO-2024216910-A1 HIGH-CHEMICAL-RESISTANCE POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 明士(北京)新材料开发有限公司 2024-10-24 WO claimed
CN-117186403-B Negative photosensitive resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2024-04-02 CN claimed
CN-116836388-B Positive photosensitive resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2023-12-15 CN claimed
CN-117186403-A Negative photosensitive resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-12-08 CN claimed
CN-116836388-A Positive photosensitive resin, resin composition, preparation method and application thereof 明士(北京)新材料开发有限公司 2023-10-03 CN claimed
CN-116149140-B Positive photosensitive resin composition with high chemical resistance and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-07-14 CN claimed
CN-116068852-B Positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-07-14 CN claimed
CN-116149140-A Positive photosensitive resin composition with high chemical resistance and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-05-23 CN claimed
CN-116068852-A Positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-05-05 CN claimed
CN-114995060-B Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-11-01 CN claimed
CN-114995061-B Low-water-absorption positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-11-01 CN claimed
CN-115220305-A Positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-10-21 CN claimed
CN-114995061-A Low-water-absorption positive photosensitive resin composition and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-09-02 CN claimed
CN-114995060-A Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-09-02 CN claimed
CN-119330839-A Method for preparing p-aminophenylacetylene 金泰旭化学技术(无锡)有限公司 2025-01-21 CN disclosed
CN-119330839-A Method for preparing p-aminophenylacetylene 金泰旭化学技术(无锡)有限公司 2025-01-21 CN disclosed
US-4219679-A HIGH CONVERSION GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-08-26 US disclosed
US-4216341-A Selective hydrogenation of certain nitroaromatic hydroxy substituted acetylenes over a heterogeneous RuS2 catalyst GULF RESEARCH & DEVELOPMENT COMPANY (US) 1980-08-05 US disclosed
US-4139561-A RUTHENIUM HYDROGENATION CATALYST GULF RESEARCH & DEVELOPMENT COMPANY (US) 1979-02-13 US disclosed