Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265179 | 0.87 | GABRA5 (0.43) | — | |
| SCHEMBL28401685 | 0.84 | — | — | |
| SCHEMBL12224105 | 0.78 | PPM1B (0.43) | L3MBTL1ALDH1A1 | |
| SCHEMBL11690602 | 0.77 | SMN1; SMN2 (0.47) | — | |
| SCHEMBL5947153 | 0.75 | GLS (0.47) | HPGD | |
| SCHEMBL9855163 | 0.75 | NAAA (0.48) | L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6019680 | 0.75 | SMN1; SMN2 (0.46) | L3MBTL1ALDH1A1KMT2AHPGD | |
| SCHEMBL17395272 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL30505304 | 0.74 | CYP3A4 (0.48) | ALDH1A1KMT2AMAPK1 | |
| SCHEMBL2721040 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |