Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13252309 | 1.00 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15987829 | 0.76 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15987828 | 0.76 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27819239 | 0.74 | MAPT (0.76) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23336404 | 0.73 | P2RX1 (0.76) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15992413 | 0.71 | MAPT (0.80) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| Phosphoric Acid SCHEMBL28511104 | 0.70 | P2RX1 (0.70) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8633084 | 0.69 | SMN1; SMN2 (0.77) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL8633080 | 0.69 | SMN1; SMN2 (0.77) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL23928548 | 0.68 | ALDH1A1 (0.63) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179203-A1 | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-07-15 | — | — | US | disclosed |
| EP-2176228-A1 | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-04-21 | — | — | EP | disclosed |
| WO-2009003921-A1 | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179203-A1 | NOVEL PYRAZOLE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNN3, KCNJ2, KCNK3 | MEN1 3396/4885KMT2A 1537/4885MAPT 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.