Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058309 | 1.00 | SPHK1 (0.48) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL10276905 | 1.00 | SPHK1 (0.48) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL10181292 | 1.00 | SPHK1 (0.48) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| SCHEMBL27841408 | 1.00 | SPHK1 (0.48) | SPHK1GPR84FFAR1LMNAOPRM1 | |
| Propylene Glycol SCHEMBL7581348 | 0.92 | LMNA (0.47) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| Glycerin SCHEMBL8149754 | 0.90 | USP2 (0.46) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL6668019 | 0.89 | FFAR1 (0.45) | FFAR1LMNAGMNNPOLBBLM | |
| SCHEMBL3259630 | 0.88 | GPR84 (0.54) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL2678966 | 0.88 | GPR84 (0.54) | SPHK1GPR84FFAR1LMNACYP2D6 | |
| SCHEMBL2978279 | 0.88 | GPR84 (0.54) | SPHK1GPR84FFAR1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328246-B1 | HIGH OIL CLEAR EMULSION WITH DIENE ELASTOMER | COLGATE PALMOLIVE CO (US) | 2006-03-01 | — | — | EP | claimed |
| EP-1492495-A1 | CLEAR ANTIPERSPIRANT WITH ALCOHOL FREE ACTIVE | Colgate-Palmolive Company (US) | 2005-01-05 | — | — | EP | claimed |
| EP-1432398-A1 | UNDERARM GEL PRODUCTS WITH SUPERABSORBENT POLYMER COMPONENT | Colgate-Palmolive Company (US) | 2004-06-30 | — | — | EP | claimed |
| EP-1432382-A1 | HIGH EFFICACY LIQUID GEL ANTIPERSPIRANT PRODUCT | Colgate-Palmolive Company (US) | 2004-06-30 | — | — | EP | claimed |
| US-20040120917-A1 | Cosmetic or dermopharmaceutical composition comprising an enzyme which is insoluble in an aqueous medium, as well as its uses | COLETICA (FR) | 2004-06-24 | — | — | US | claimed |
| WO-2003086339-A1 | CLEAR ANTIPERSPIRANT WITH ALCOHOL FREE ACTIVE | COLGATE-PALMOLIVE COMPANY (US) | 2003-10-23 | — | — | WO | claimed |
| EP-1328246-A2 | HIGH OIL CLEAR EMULSION WITH DIENE ELASTOMER | Colgate-Palmolive Company (US) | 2003-07-23 | — | — | EP | claimed |
| EP-1326582-A2 | HIGH OIL CLEAR EMULSION WITH ELASTOMER | Colgate-Palmolive Company (US) | 2003-07-16 | — | — | EP | claimed |
| WO-2003030854-A1 | UNDERARM GEL PRODUCTS WITH SUPERABSORBENT POLYMER COMPONENT | COLGATE-PALMOLIVE COMPANY (US) | 2003-04-17 | — | — | WO | claimed |
| WO-2003030840-A1 | HIGH EFFICACY LIQUID GEL ANTIPERSPIRANT PRODUCT | COLGATE-PALMOLIVE COMPANY (US) | 2003-04-17 | — | — | WO | claimed |
| US-6500412-B1 | FREE OF ADDED ETHANOL AND PROPYLENE GLYCOL, AND IS FREE OF ELASTOMER, SOAP AND BORATE GELLING AGENTS | COLGATE-PALMOLIVE COMPANY | 2002-12-31 | — | — | US | claimed |
| US-6485716-B1 | HIGH EFFICACY GEL COMPOSITION WHICH IS A LOW VISCOSITY LIQUID EMULSION, IS ELASTOMER-FREE, AND WHICH COMPRISES AN ANTIPERSPIRANT ACTIVE (PREFERABLY WITH A LOWER METAL TO CHLORIDE RATIO) AND A REDUCED AMOUNT OF SURFACTANT | COLGATE-PALMOLIVE COMPANY | 2002-11-26 | — | — | US | claimed |
| WO-2002060403-A2 | HIGH OIL CLEAR EMULSION WITH ELASTOMER | COLGATE-PALMOLIVE COMPANY (US) | 2002-08-08 | — | — | WO | claimed |
| US-6426062-B1 | MIXTURE OF STARCH GRAFT POLYMER, SILICONE AND GELATION AGENT | COLGATE-PALMOLIVE COMPANY | 2002-07-30 | — | — | US | claimed |
| US-6403069-B1 | SILICONE, ANTIPERSPIRANT, SOLVENT AND EMULSIFIER | COLGATE-PALMOLIVE COMPANY | 2002-06-11 | — | — | US | claimed |
| US-6387357-B1 | CYCLOMETHICONE OR DIMETHICONE CROSSPOLYMER OF A POLYSILOXANE AND AN ALPHA, OMEGA DIENE; A SILICONE COPOLYOL; A VOLATILE SILICONE; ANTIPERSPIRANT AND/OR DEODORANT WATER IN OIL EMULSION | COLGATE-PALMOLIVE COMPANY | 2002-05-14 | — | — | US | claimed |
| WO-2002034212-A2 | HIGH OIL CLEAR EMULSION WITH DIENE ELASTOMER | COLGATE-PALMOLIVE COMPANY (US) | 2002-05-02 | — | — | WO | claimed |
| US-12629327-B2 | Keratin-based hair straightening formulations, methods and systems | BEAUTY BIOLABS LLC (US) | 2026-05-19 | — | — | US | disclosed |
| EP-0809483-A1 | PROCESS FOR INHIBITING SORBATE-INDUCED BROWN DISCOLORATIONS IN COSMETICS AND FOODSTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025140-A1 | PROCESS FOR INHIBITING SORBATE-INDUCED BROWN DISCOLORATIONS IN COSMETICS AND FOODSTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12629327-B2 | Keratin-based hair straightening formulations, methods and systems | KRT18, HCN4, COL14A1 | SPHK1 1985/4885GPR84 4079/4885FFAR1 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.