SCHEMBL344997

SCHEMBL344997

CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC(C)C

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.55
TSHR P16473 1/20 0.53
THRB P10828 1/20 0.53
LMNA P02545 2/20 0.53
DNM1 Q05193 2/20 0.50
SPHK1 Q9NYA1 1/20 0.50
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH4 P08319 1/20 0.46
ADH7 P40394 1/20 0.46
PLA2G1B P04054 1/20 0.46
PLA2G2A P14555 1/20 0.46
ACE2 Q9BYF1 1/20 0.44
FDPS P14324 3/20 0.44
GPR84 Q9NQS5 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3002559 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
SCHEMBL3223191 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
SCHEMBL671913 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
SCHEMBL6122664 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
SCHEMBL15148 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
SCHEMBL157759 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
Hexadecane SCHEMBL23000686 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
Octane SCHEMBL7455770 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
SCHEMBL22950680 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1
SCHEMBL598884 1.00 OPRM1 (0.55) OPRM1TSHRTHRBLMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999038485-A1 COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-08-05 WO claimed
US-5919467-A BRANCHED CHAIN ALIPHATIC HYDROCARBON, POLYETHYLENE PARTICLES, CROSSLINKED ACRYLATE POLYMER, ALKYLMETHYLSILOXANE THE PROCTOR & GAMBLE COMPANY (US) 1999-07-06 US claimed
WO-1996015762-A1 COSMETIC COMPOSITIONS IN STICK FORM THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO claimed
WO-1996015760-A1 COSMETIC COMPOSITIONS IN STICK FORM THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO claimed
WO-1996015761-A1 COSMETIC COMPOSITIONS IN STICK FORM THE PROCTER & GAMBLE COMPANY (US) 1996-05-30 WO claimed
US-20210236403-A1 COSMETIC, PERSONAL CARE, AND CLEANING PRODUCTS Planet Lindsay, LLC (US) 2021-08-05 US disclosed
US-10682383-B2 Personal care compositions with improved hyposensitivity THE PROCTER & GAMBLE COMPANY (US) 2020-06-16 US disclosed
US-20190111095-A1 Personal Care Compositions With Improved Hyposensitivity PROCTER & GAMBLE (US) 2019-04-18 US disclosed
US-10183051-B2 Personal care compositions with improved hyposensitivity THE PROCTER & GAMBLE COMPANY (US) 2019-01-22 US disclosed
US-20170128512-A1 Personal Care Compositions With Improved Hyposensitivity PROCTER & GAMBLE (US) 2017-05-11 US disclosed
US-9585866-B2 Personal care compositions with improved hyposensitivity THE PROCTER & GAMBLE COMPANY (US) 2017-03-07 US disclosed
US-9084734-B2 Peptide personal care compositions and methods for their use DANISCO US INC. (US) 2015-07-21 US disclosed
WO-1998050005-A1 COMPOSITIONS FOR COSMETIC APPLICATIONS MEDLOGIC GLOBAL CORPORATION (US) 1998-11-12 WO disclosed
EP-0785763-A4 1997-07-30 EP disclosed
EP-0785763-A1 POWDER COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-30 EP disclosed
EP-0752845-A4 POWDER COSMETIC COMPOSITIONS PROCTER & GAMBLE (US) 1997-03-19 EP disclosed
EP-0752845-A1 POWDER COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-01-15 EP disclosed
EP-0500423-B1 Cleansing composition containing synthetic oil and method for carrying it out OREAL (FR) 1996-01-24 EP disclosed
WO-1995025503-A1 POWDER COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-09-28 WO disclosed
WO-1995025499-A1 POWDER COSMETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10682383-B2 Personal care compositions with improved hyposensitivity CUTA, DPM1, PIEZO1 OPRM1 3922/4885TSHR 3458/4885THRB 986/4885
US-20190111095-A1 Personal Care Compositions With Improved Hyposensitivity CUTA, DPM1, PIEZO1 OPRM1 3922/4885TSHR 3458/4885THRB 986/4885
US-10183051-B2 Personal care compositions with improved hyposensitivity CUTA, DPM1, PIEZO1 OPRM1 3922/4885TSHR 3458/4885THRB 986/4885
US-20170128512-A1 Personal Care Compositions With Improved Hyposensitivity CUTA, DPM1, PIEZO1 OPRM1 3922/4885TSHR 3458/4885THRB 986/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.