Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.47 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046578 | 0.96 | MMP13 (0.51) | MMP13MEN1KMT2ASCN5ASCN2A | |
| SCHEMBL3451181 | 0.87 | SCN5A (0.43) | MMP13SCN5ASCN2ASCN10ARAB9A | |
| SCHEMBL3453027 | 0.87 | PTPN1 (0.53) | MMP13MEN1KMT2ASCN5ASCN2A | |
| SCHEMBL3451824 | 0.84 | RAB9A (0.50) | SCN5ASCN2ASCN10ARAB9ANPC1 | |
| SCHEMBL4048359 | 0.83 | NQO2 (0.54) | RAB9ANPC1CHRNA4SMN1; SMN2 | |
| SCHEMBL4047306 | 0.82 | RAB9A (0.44) | MMP13SCN5ASCN2ASCN10ARAB9A | |
| SCHEMBL3451493 | 0.81 | RAB9A (0.71) | MEN1KMT2ASCN5ASCN2ASCN10A | |
| Hydrochloric Acid SCHEMBL3451329 | 0.80 | RAB9A (0.69) | MEN1KMT2ASCN5ASCN2ASCN10A | |
| SCHEMBL4050262 | 0.79 | RAB9A (0.52) | SCN5ASCN2ASCN10ARAB9ANPC1 | |
| SCHEMBL4048361 | 0.76 | RAB9A (0.73) | MEN1KMT2ARAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855208-B2 | 3, 9-diazabicyclo(3.3.1)non-3-yl-aryl methanone derivatives as nicotinic acetylcholine receptor agonists | NEUROSEARCH A/S (DK) | 2010-12-21 | — | — | US | claimed |
| US-20100234384-A1 | 3, 9-DIAZABICYCLO(3.3.1)NON-3-YL-ARYL METHANONE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | ANIONA APS (DK) | 2010-09-16 | — | — | US | claimed |
| US-7855208-B2 | 3, 9-diazabicyclo(3.3.1)non-3-yl-aryl methanone derivatives as nicotinic acetylcholine receptor agonists | NEUROSEARCH A/S (DK) | 2010-12-21 | — | — | US | disclosed |
| US-20100234384-A1 | 3, 9-DIAZABICYCLO(3.3.1)NON-3-YL-ARYL METHANONE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | ANIONA APS (DK) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234384-A1 | 3, 9-DIAZABICYCLO(3.3.1)NON-3-YL-ARYL METHANONE DERIVATIVES AS NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS | CHRNA3, CHRNA6, CHRNA10 | MMP13 2001/4885MEN1 3168/4885KMT2A 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.